Product peptide-amyloid-peptides

Home > products > peptide> amyloid-peptides

Catalog	name	Description	price
R-M-1454	Beta Amyloid [1-28] Peptide,Cas:109770-29-8	Beta-amyloid production results from cleavage in the extracellular domain of APP by the beta-secretase (BACE1) , which results in the production of the APP C-terminal fragment C99. This fragment is further cleaved by the gamma-secretase at residues 40-42 to produce beta-amyloid 40 and 42 peptides. Beta-amyloid aggregation and neuritic plaque formation are pathologic hallmarks of Alzheimer disease. This peptide corresponds to the human beta-amyloid 1-28 peptide.	price>
R-M-1455	Beta Amyloid [1-40] Peptide,CAS: 131438-79-4	Beta-amyloid production results from cleavage in the extracellular domain of APP by the beta-secretase (BACE1) , which results in the production of the APP C-terminal fragment C99. This fragment is further cleaved by the gamma-secretase at residues 40-42 to produce beta-amyloid 40 and 42 peptides. Beta-amyloid aggregation and neuritic plaque formation are pathologic hallmarks of Alzheimer disease. This peptide corresponds to the human beta-amyloid 1-40 peptide.	price>
R-M-1491	AMYLIN (8-37), HUMAN,Cas: 135702-23-7	Amylin is also known as islet amyloid precursor peptide (IAPP) and is co-secreted with insulin from pancreatic β-cells. Amylin is an endogenous peptide hormone that exhibits gastrointestinal motility modulating activity, decreasing gastric emptying and suppressing gastric acid secretion; these actions slow food intake, preventing blood glucose spikes after eating and decreasing insulin demand. Misguided IAPP processing plays a significant role in the development of diabetes mellitus type 2. Like calcitonin, IAPP inhibits osteoclast activity and Ca2+ reabsorption in bones. This peptide binds to calcitonin-RAMP complexes.	price>
R-M-1492	AMYLIN (8-37), RAT,Cas:138398-61-5	Amylin is also known as islet amyloid precursor peptide (IAPP) and is co-secreted with insulin from pancreatic β-cells. Amylin is an endogenous peptide hormone that exhibits gastrointestinal motility modulating activity, decreasing gastric emptying and suppressing gastric acid secretion; these actions slow food intake, preventing blood glucose spikes after eating and decreasing insulin demand. Misguided IAPP processing plays a significant role in the development of diabetes mellitus type 2. Like calcitonin, IAPP inhibits osteoclast activity and Ca2+ reabsorption in bones. This peptide binds to calcitonin-RAMP complexes.	price>
R-M-1493	AMYLIN, CAT,Cas:124447-81-0	Amylin is also known as islet amyloid precursor peptide (IAPP) and is co-secreted with insulin from pancreatic β-cells. Amylin is an endogenous peptide hormone that exhibits gastrointestinal motility modulating activity, decreasing gastric emptying and suppressing gastric acid secretion; these actions slow food intake, preventing blood glucose spikes after eating and decreasing insulin demand. Misguided IAPP processing plays a significant role in the development of diabetes mellitus type 2. Like calcitonin, IAPP inhibits osteoclast activity and Ca2+ reabsorption in bones. This peptide binds to calcitonin-RAMP complexes.	price>
R-M-1494	AMYLIN, HUMAN,Cas :122384-88-7	Amylin is also known as islet amyloid precursor peptide (IAPP) and is co-secreted with insulin from pancreatic β-cells. Amylin is an endogenous peptide hormone that exhibits gastrointestinal motility modulating activity, decreasing gastric emptying and suppressing gastric acid secretion; these actions slow food intake, preventing blood glucose spikes after eating and decreasing insulin demand. Misguided IAPP processing plays a significant role in the development of diabetes mellitus type 2. Like calcitonin, IAPP inhibits osteoclast activity and Ca2+ reabsorption in bones. This peptide binds to calcitonin-RAMP complexes.	price>
R-M-1495	AMYLOID-Β (1-40),Cas :131438-79-4	Amyloid-β (Aβ) is a peptide cleavage product of amyloid precursor protein (APP) that is often used as a biomarker in Alzheimer disease. Misfolded Aβ oligomers instigate conformation changes in other, normally folded Aβ oligomers, increasing the number of misfolded proteins and eventually forming neurotoxic plaques. These plaques impair cognitive performance in vivo. Aβ (1-42) is more fibrillogenic and more highly associated with Alzheimer disease than Aβ (1-40), although the shorter form is more common.	price>
R-M-1496	AMYLOID-Β (25-35),Cas:131602-53-4	Amyloid-β (Aβ) is a peptide cleavage product of amyloid precursor protein (APP) that is often used as a biomarker in Alzheimer’s disease. Misfolded Aβ oligomers instigate conformation changes in other, normally folded Aβ oligomers, increasing the number of misfolded proteins and eventually forming neurotoxic plaques. These plaques impair cognitive performance in vivo.	price>
R-M-1548	Beta-Amyloid (12-20),CAS :134649-29-9	β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Amino acids 12-20 of the amyloid beta peptide, a key subunit of extracellular plaques found in the brains of patients with Alzheimer’s disease.	price>
R-M-1549	Biotin-β Amyloid (1-42) Human,Cas:102577-21-9	Amino acids 1-42 of amyloid beta protein, a key subunit of extracellular plaques found in the brains of patients with Alzheimer’s disease. Contains covalently attached N-Terminal Biotin tag for con-venient detection and purification.	price>

...