Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00566	UCN-02,cas:121569-61-7	UCN-02 (7-epi-Hydroxystaurosporine)(C28H26N4O4,482.53) is a selective protein kinase C (PKC) inhibitor produced by Streptomyces strain N-12, with IC50s of 62 nM and 250 nM for PKC and protein kinase A (PKA), respectively.	price>
R-XASYS-00567	7-xylosyltaxol,cas:90332-66-4	7-xylosyltaxol(Taxol-7-xyloside)(C52H59NO18,986.0) is a taxol (Paclitaxel) derivative; Paclitaxel binds to tubulin and inhibits the disassembly of microtubules.	price>
R-XASYS-00568	8-Hydroxyguanosine,cas:3868-31-3	8-Hydroxyguanosine(C10H13N5O6,299.2) is an oxidized nucleoside and a marker of RNA oxidative damage.Levels of 8-hydroxyguanosine increase in HeLa cells in a concentration-dependent manner when cultured with hydrogen peroxide.	price>
R-XASYS-00569	9-Azido-Neu5DAz,cas:1639411-87-2	9-Azido-Neu5DAz(C14H22N6O8,402.36) is a non-natural bifunctional carbohydrates as imaging agent.	price>
R-XASYS-00570	A 419259 trihydrochloride,cas:1435934-25-0	A-419259 is an inhibitor of Src family kinases, including Src, LCK, Lyn, and Hck (IC50s = 9,<3,<3, and 11.26nM,respectively).It is selective for these kinases over c-Abl (IC50 = 3,000 nM) and PKC (IC50 = >33μM).A-419259 inhibits growth of Philadelphia chromosome-positive (Ph+) K-562 and Meg-01 myeloid leukemia cells (IC50s = 0.1-0.3 and 0.1μM, respectively)	price>
R-XASYS-00571	A 438079,cas:899507-36-9	A-438079(C13H9Cl2N5,342.6) is a competitive antagonist of the nucleotide receptor P2X7 (pIC50 = 6.9).It inhibits both calcium flux and IL-1β release mediated by P2X7 while not affecting the activity of other P2X receptors.A-438079 is effective in evaluating the role of P2X7 in nociception, oxidative stress, and apoptosis in cells and animals.	price>
R-XASYS-00572	A-1331852,cas:1430844-80-6	A-1331852(C38H38N6O3S,658.82) is an orally bioavailable Bcl-xL inhibitor that selectively binds Bcl-xL over Bcl-2, Mcl-1, and Bcl-W (Kis = <0.01, 6, 142, and 4 nM, respectively).1 It inhibits growth of Bcl-xL-dependent MOLT-4, but not Bcl-2-dependent RS4;11, acute lymphocytic leukemia cells in vitro (EC50s = 6 and >5,000 nM, respectively).	price>
R-XASYS-00573	A-366,cas:1527503-11-2	A-366 is a potent, peptide-competitive inhibitor of the lysine methyltransferase G9a (IC50 = 3.3 nM).It displays greater than 1,000-fold selectivity over 21 other methyltransferases.A-366 significantly reduces the cellular levels of dimethylation on histone 3 at lysine 9 (H3K9Me2) in PC3 cells without reducing total histone 3, H3K27Me3, or H3K36Me2.	price>
R-XASYS-00574	A-381393,cas:726174-00-1	2-[[4-(3,4-dimethylphenyl)piperazin-1-yl]methyl]-1H-benzimidazole (2-DPMB)(C20H24N4,320.4) is a heterocyclic compound belonging to the benzimidazole family. It is a synthetic aromatic compound with a wide range of biological activities. It has been widely studied and used in scientific research as an inhibitor of enzymes, such as human immunodeficiency virus (HIV) protease, and as a ligand for G-protein-coupled receptors (GPCRs).	price>
R-XASYS-00575	A-385358,cas:406228-55-5	A-385358(C32H41N5O5S2,639.83) is an inhibitor of Bcl-XL, a novel target for the treatment of many cancer types. A-385358 enhances the in vitro cytotoxic activity of numerous chemotherapeutic agents (paclitaxel, etoposide, cisplatin, and doxorubicin) in several tumor cell lines.	price>

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