A 419259 trihydrochloride,cas:1435934-25-0
7-[trans-4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, trihydrochloride
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-XASYS-00570 | 5mg | 441.00 | + Add to cart |
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R-XASYS-00570 | 10mg | 614.00 | + Add to cart |
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Product description
A-419259 is an inhibitor of Src family kinases, including Src, LCK, Lyn, and Hck (IC50s = 9,<3,<3, and 11.26nM,respectively).It is selective for these kinases over c-Abl (IC50 = 3,000 nM) and PKC (IC50 = >33μM).A-419259 inhibits growth of Philadelphia chromosome-positive (Ph+) K-562 and Meg-01 myeloid leukemia cells (IC50s = 0.1-0.3 and 0.1μM, respectively)
Appearance | N/A |
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Molecular Weight | N/A |
Purity | >90% |
Solubility | N/A |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 3 weeks |
Stability | 1 year |
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