Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00476	N-Desmethyltamoxifen,cas:31750-48-8	N-Desmethyltamoxifen(C25H27NO,357.49), the major metabolite of Tamoxifen in humans and a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen, also is a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.	price>
R-XASYS-00477	NG-52,cas:212779-48-1	NG 52(C16H19ClN6O,346.8) is a tri-substituted purine that binds to the ATP-binding site of yeast cyclin-dependent kinases, inhibiting Cdc28p and Pho85p (IC50s = 7 and 2 µM, respectively).It is ineffective against the yeast kinases Kin28p, Srb10, and Cak1p. NG 52 is cell permeable and inhibits the growth of S. cerevisiae (GI50 = 30 µM).	price>
R-XASYS-00478	NOS-IN-1,cas:165383-72-2	2-Imino-4-methylpiperidine (acetate)(C8H16N2O2,178.22) is a 2-iminopiperidine class of NOS inhibitor. In the presence of a final L-arginine concentration of 30 μM, 2-Imino-4-methylpiperidine inhibited human iNOS, eNOS, and nNOS with IC50 values of 0.1, 1.1, and 0.2 μM, respectively. 2-Imino-4-methylpiperidine exhibited 9-fold and 1-fold selectivity for iNOS compared to eNOS and nNOS, respectively.	price>
R-XASYS-00479	Gefitinib impurity 2,cas:246512-44-7	Gefitinib impurity 2(C15H23N3O4,309.36) is the impurity of Gefitinib. Gefitinib is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity	price>
R-XASYS-00480	PKC-iota inhibitor 1,cas:2328094-11-5	PKC-iota inhibitor 1(C21H22N6O,374.44) (compound 19) is a protein kinase C-iota inhibitor with an IC50 value of 0.34μM.	price>
R-XASYS-00481	2-Hydroxy atorvastatin calcium salt,cas:265989-46-6	2-hydroxy Atorvastatin(C33H37CaFN2O6,593.7) is an active metabolite of the HMG-CoA reductase inhibitor atorvastatin.2-hydroxy Atorvastatin is formed from atorvastatin by the cytochrome P450 (CYP) isoform CYP3A4. It inhibits lipid hydroperoxide formation and copper sulfate-induced thiobarbituric acid reactive substances (TBARS) formation in 1,2-dilinoleoyl-sn-glycero-3-PC	price>
R-XASYS-00482	BV02,cas:292870-53-2	BV02(C20H15N3O5,377.35) is a potent 4-3-3 PPI (14-3-3 protein-protein interaction) inhibitor. BV02 shows cytotoxicity for hematopoietic cells expressing the IM (imatinib mesylate)-sensitive wild type Bcr-Abl and the IM-resistant T315I mutation. BV02 has the potential for the research of chronic myeloid leukemia.	price>
R-XASYS-00483	20-O-Acetylingenol-3-angelate,cas:82425-35-2	20-O-Acetylingenol-3-angelate(C27H36O7,472.57) (Euphorbia factor Pe1) is a natural compound.	price>
R-XASYS-00484	24,25-Dihydroxy VD2,cas:58050-55-8	24,25-Dihydroxy VD2(C28H44O3,428.65) is a hydroxylated metabolite of Vitamin D2; a synthetic analog of Vitamin D.	price>
R-XASYS-00485	24-Hydroxycholesterol,cas:30271-38-6	24-Hydroxycholesterol(C27H46O2,402.65) is a natural sterol, which serves as a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR, and a potent activator of the transcription factors LXR.24S-hydroxycholesterol oxysterol-generating enzyme Cyp46a1 is overexpressed during the angiogenic switch in rat insulin promoter 1-T-antigen 2 (RIP1-Tag2) pNET formation	price>

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