Gefitinib impurity 2,cas:246512-44-7

Gefitinib impurity 2(C15H23N3O4,309.36) is the impurity of Gefitinib. Gefitinib is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity

msds of 2-Amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]benzamide