Catalog |
name |
Description |
price |
R-XASYS-00486 |
24-Norursodeoxycholic acid,cas:99697-24-2 |
24-norursodeoxycholic acid(C23H38O4,378.6) is a side chain-shortened C23 homolog of UDCA.It has shown potent anti-inflammatory, anti-cholestatic, and anti-fibrotic properties.It is a Ursodeoxycholic Acid derivative. It is superior to Ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice |
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R-XASYS-00487 |
24R-Calcipotriol,cas:112827-99-3 |
24R-Calcipotriol(PRI 2202)(C27H40O3,412.6) is an impurity of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors. |
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R-XASYS-00488 |
2614W94,cas:205187-35-5 |
2614W94(C15H11F3O4S,344.31) is a selective, reversible inhibitor of monoamine oxidase-A with a competitive mechanism of inhibition and IC50 of 5 nM and Ki of 1.6 nM with serotonin as substrate. |
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R-XASYS-00489 |
2OH-BNPP1,cas:833481-73-5 |
2OH-BNPP1(C16H19N5O,297.35) is an inhibitor of BUB1 kinase, a Ser/Thr kinase, used for the treatment of cancer. |
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R-XASYS-00490 |
2R,4R-Sacubitril,cas:766480-48-2 |
2R,4R-Sacubitril(C24H29NO5,411.49) is the impurity of Sacubitril. Sacubitril is approved by the Food and Drug Administration for use in combination with valsartan for the treatment of patients with heart failure. |
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R-XASYS-00491 |
U-0521,cas:5466-89-7 |
U-0521 is an inhibitor of catechol-O-methyltransferase (COMT; Ki = 7.8 µM for the rat liver enzyme) and tyrosine hydroxylase (IC50 =1 µM for the rabbit adrenal enzyme).It enhances epinephrine-induced contractions of isolated rabbit atria when used at a concentration of 55 µM. |
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R-XASYS-00492 |
Zidovudine O-β-D-glucuronide sodium,cas:133525-01-6 |
Zidovudine O-β-D-glucuronide (3-Azido-3-deoxythymidineβ-D-glucuronide) sodium(C16H20N5NaO10,465.4) is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. |
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R-XASYS-00493 |
3-Hydroxypterostilbene,cas:475231-21-1 |
3-Hydroxypterostilbene(C16H16O4,272.30) is a Pterostilbene (HY-N0828) analogue. 3-Hydroxypterostilbene inhibits the growth of COLO 205, HCT-116 and HT-29 cells with IC50s of 9.0, 40.2 and 70.9 µM, respectively. 3-Hydroxypterostilbene significantly down-regulates PI3K/Akt and MAPKs signaling pathways and effectively inhibits the growth of human colon cancer cells by inducing apoptosis and autophagy. 3-Hydroxypterostilbene can be used for the research of cancer. |
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R-XASYS-00494 |
3,4,5-Trihydroxycinnamic acid decyl ester,cas:1770778-45-4 |
3,4,5-Trihydroxycinnamic acid decyl ester(C19H28O5,336.42) is an excellent inhibitor of lipid absorption and accumulation, with anti-obesity properties. 3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor, with an EC50 of approximately 0.9μM. |
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R-XASYS-00495 |
kbNB142-70,cas:1233533-04-4 |
kb NB 142-70(C11H9NO2S2,251.3) is a selective inhibitor of protein kinase D (PKD) with IC50 values of 28.3, 58.7, and 53.2 nM for PKD1, 2, and 3, respectively.1 It has been shown to inhibit prostate cancer cell migration and invasion, as well as reduce wound healing in vitro. |
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