Home > Keywords >
Catalog | name | Description | price |
---|---|---|---|
R-C-257 | DSPE-S-S-PEG-NPC | It is a linear cross functional PEGylation reagent containing DSPE phospholipids and NPC.It is an effective self-assembly reagent for the preparation of polyethylene glycol liposomes or micelles, and also provides a NPC group coupled with thiol molecules.It is commonly used in targeted drug delivery. Lipid bilayer improves the solubility of drugs.Peg provides stealth,prolongs the half-life of circulation,and reduces nonspecific protein binding or cell adhesion.Acid groups are used to bind targeted molecules,including antibodies,aptamers,proteins and peptides. | price> |
R-R-1255 | TAK-243 CAS No.1450833-55-2 | TAK-243 (MLN7243)/CAS No.1450833-55-2 is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor (IC50=1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global protein ubiquitination. TAK-243 (MLN7243) induces endoplasmic reticulum (ER) stress, abrogates NF-κB pathway activation and promotes apoptosis. | price> |
R-PL-0193 | Cholesterol-PEG-ISC | Cholesterol-polyethylene glycol-Isocyanate,Cholesterol-PEG-ISC from ruixi Block copolymers Cholesterol-PEG-ISC.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. | price> |
R-C-258 | DSPE-S-S-PEG-cRGD | The crgd in phospholipid peg crgd is a five membered cyclic peptide,which can be used for passive targeting,active targeting research and drug delivery of micelles and vesicles.DSPE(1,2-distearyl-sn-glycerin-3-phosphate ethanolamine) is a saturated 18 carbon phospholipid, which is commonly used in the synthesis of liposomes.Polyethylene glycol (PEG)-coupled DSPE is hydrophilic and can be used for drug delivery,gene transfection and biomolecular modification.PEGylation of phospholipid significantly improved the blood circulation time and stability of capsule drugs. | price> |
R-R-1256 | Lidocaine-d10 hydrochloride CAS No.1189959-13-4 | Lidocaine-d10 (hydrochloride)/CAS No.1189959-13-4 is the deuterium labeled Lidocaine hydrochloride. Lidocaine hydrochloride (Lignocaine hydrochloride) inhibits sodium channels involving complex voltage and using dependence. Lidocaine hydrochloride decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine hydrochloride, an amide derivative, has the potential for the research of the ventricular arrhythmia. | price> |
R-OF-001 | Ovalbumin-FITC | Ovalbumin-Fluorescein,Ovalbumin-FITC FITC-Ovalbumin from ruixi Ovalbumin (abbreviated OVA) is the main protein found in egg white. Ovalbumin has been used in the study of protein structure, proteomics and immunology. Ruixibio provides a variety of functionalized and bioconjugated ovalbumin conjugates.These labeled ovalbumin products were purified by size exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo. | price> |
R-C-259 | DSPE-PEG2000-benzylguanine | Peg is a linear polymer material which is polymerized by ethylene glycol monomer. In PEG lipid complex,due to the weak connection between PEG or PEG stearic acid and liposome,it can not effectively reduce the uptake of res to liposome.The ability of PEG dipalmitoyl phosphatidylglyceride and PEG cholesterol to prolong the half-life of liposomes was stronger than that of PEG or PEG stearic acid alone,but lower than DSPE-PEG.Peg and DSPE are connected by carbamate bond,and there are two saturated acyl chains.The lipophilic end is DSPE and the hydrophilic end is peg.The connection between PEG and DSPE is firm, and the ability to protect the liposome from being destroyed is the strongest. | price> |
R-R-1257 | EUK-134 CAS No.81065-76-1 | EUK-134/CAS No.81065-76-1, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion-induced damage. EUK-134 is a superoxide dismutase (SOD) mimetics (SODm) with catalase activity. EUK-134 is a mitoprotective antioxidant. EUK-134 reduces the expression of NF-κB, MDA level, and protein carbonylation in H9C2 cells. | price> |
R-OR-002 | Ovalbumin-CY3 | Ovalbumin-Cyanine3,Ovalbumin-CY3 CY3-Ovalbumin from ruixi Ovalbumin (abbreviated OVA) is the main protein found in egg white. Ovalbumin has been used in the study of protein structure, proteomics and immunology. Ruixibio provides a variety of functionalized and bioconjugated ovalbumin conjugates.These labeled ovalbumin products were purified by size exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo. | price> |
R-C-260 | DOPE-PEG-CY5 | Cy5 fluorescent dyes:dyes that emit fluorescence.Cy5 fluorescent dyes can be used alone or combined into compound fluorescent dyes.The compound fluorescent dye is a kind of fluorescent dye synthesized by fluorescence resonance energy transfer technology.It is composed of a donor and a acceptor fluorescent molecule which is very close and energy can be transferred between each other.It can be used in medical research,drug release,nanotechnology and new materials research,cell culture.And the active compounds such as ligand research,peptide synthesis support,graft polymer,new materials and polyethylene glycol modified functional coating. | price> |
R-R-1258 | Nimbolide CAS No.25990-37-8 | Nimbolide/CAS No.25990-37-8 is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways. | price> |
R-OF-003 | Ovalbumin-CY5 | Ovalbumin-Cyanine5,Ovalbumin-CY5 CY5-Ovalbumin from ruixi Ovalbumin (abbreviated OVA) is the main protein found in egg white. Ovalbumin has been used in the study of protein structure, proteomics and immunology. Ruixibio provides a variety of functionalized and bioconjugated ovalbumin conjugates.These labeled ovalbumin products were purified by size exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo. | price> |
R-C-261 | DOPE-PEG-CY7.5 | Polyethylene glycol phospholipid is an excellent material to form liposomes, which can be used for gene transfection,vaccine delivery,drug delivery and targeted drug use.Phospholipids are hydrophobic and hydrophilic.It can be used to modify protein drugs,peptide compounds, organic small molecule drugs, biomaterials and so on.Cy7.5 is a fluorescent imaging agent (ex=700-770nm,EM = 790nm) and magnetic resonance imaging agent. | price> |
R-R-1259 | LTbR-IN-1 CAS No.2189366-77-4 | LTβR-IN-1/CAS No.2189366-77-4 is a potent, selective lymphotoxin β receptor (LTβR) inhibitor. LTβR-IN-1 also selectively inhibits the nuclear translocation of p52 depended on TNF12A, instead of the nuclear translocation of p65 mediated by TNF-α receptor. LTβR-IN-1 regulates the NF-kB signaling pathway IN a ligand-independent manner. | price> |
R-OR-003 | Ovalbumin-CY5.5 | Ovalbumin-Cyanine5.5,Ovalbumin-CY5.5 CY5.5-Ovalbumin from ruixi Cy5.5 dyes are one type of the most common red fluorophores.Ovalbumin (abbreviated OVA) is the main protein found in egg white. Ovalbumin has been used in the study of protein structure, proteomics and immunology. | price> |
R-R-1260 | Specnuezhenide CAS No.39011-92-2 | Specnuezhenide ((8E)-Nuezhenide)/CAS No.39011-92-2 is isolated from the fruits of Ligustrum lucidum. Specnuezhenide ((8E)-Nuezhenide) can inhibit IL-1β-induced inflammation in chondrocytes via inhibition of NF-κB and wnt/β-catenin signaling. Specnuezhenide ((8E)-Nuezhenide) exerts anti-inflammatory effects in a rat model of osteoarthritis (OA). | price> |
R-OF-004 | Ovalbumin-CY7 | Ovalbumin-Cyanine7,Ovalbumin-cy7 cy7-ovalbumin from ruixi Ovalbumin (abbreviated OVA) is the main protein found in egg white. Ovalbumin has been used in the study of protein structure, proteomics and immunology. Ruixibio provides a variety of functionalized and bioconjugated ovalbumin conjugates.These labeled ovalbumin products were purified by size exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo. | price> |
R-C-263 | DSPE-PEG2000-TK-NHS | It is a useful self-assembly reagent to prepare PEGylated liposomes or micelles, and to provide NHS groups to bind with amine containing parts or ligands.It is commonly used in lipid bilayer targeted drug delivery to improve the solubility of drugs,prolong the half-life of circulation,reduce nonspecific protein binding or cell adhesion,and acid groups become biological binding target molecules including antibodies,aptamers,proteins and peptides. | price> |
R-R-1261 | Bortezomib-d8 | Bortezomib-d8 is the deuterium labeled Bortezomib. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Anti-cancer activity. | price> |
R-OR-004 | Ovalbumin-CY7.5 | Ovalbumin-Cyanine7.5,Ovalbumin-CY7.5 CY7.5-Ovalbumin from ruixi Ovalbumin (abbreviated OVA) is the main protein found in egg white. Ovalbumin has been used in the study of protein structure, proteomics and immunology. Ruixibio provides a variety of functionalized and bioconjugated ovalbumin conjugates.These labeled ovalbumin products were purified by size exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo. | price> |