Catalog |
name |
Description |
price |
R-R-0310 |
DOTA-RGD |
DOTA-RGD is a radiolabeled peptide-based compound used in molecular imaging and targeted therapy.DOTA-RGD can also be used for targeted therapy by attaching therapeutic isotopes, such as Lutetium-177, to the RGD peptide. This enables the delivery of localized radiation to tumors with high integrin receptor expression, potentially leading to the destruction of cancer cells. |
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R-R-0313 |
NOTA-E(cRGDfK)2 |
NOTA-E(cRGDfK)2 is a radiolabeled peptide-based compound used in molecular imaging and targeted therapy, with a specific focus on targeting integrin receptors commonly found in cancer cells. The compound consists of a cyclic peptide motif, cRGDfK, which possesses high affinity for integrin receptors, along with a chelator called NOTA (1,4,7-triazacyclononane-1,4,7-triacetic acid) that allows for the complexation of radioactive metals. |
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R-R-0314 |
Galacto-RGD |
Galacto-RGD/CAS.922175-70-0 is a specialized peptide that was first isolated from the laminin in the extracellular matrix of various tissues. The -RGD sequence in the name stands for the tripeptide sequence: Arginine-Glycine-Aspartic acid. This sequence is present in numerous extracellular matrix proteins, including laminin, vitronectin, and fibronectin. Together with the galactose moiety, Galacto-RGD acts as a potent inhibitor for attaching integrins, which play a crucial role in activating cell adhesion signals. |
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R-R-0315 |
[18F]FB-RGD |
[18F]FB-RGD is a radiolabeled compound used in molecular imaging and targeted therapy, particularly in the field of cancer imaging and oncology research. [18F]FB-RGD can potentially be used in targeted therapy by attaching therapeutic agents or radioisotopes to the RGD peptide, enabling the specific delivery of treatment to tumors with high integrin receptor expression. |
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R-R-0320 |
cyclic Arg(Pbf)-Gly-Asp(Ot-Bu)-D-Tyr(Ot-Bu)-Lys(NH2) |
Cyclic Arg(Pbf)-Gly-Asp(Ot-Bu)-D-Tyr(Ot-Bu)-Lys(NH2)/CAS: 903518-34-3 refers to a specific sequence of amino acids forming a cyclic peptide. Arg-Gly-Asp-Tyr-Lys in this peptide is of particular interest in the field of peptide chemistry and molecular biology, as it is a component of the RGD (Arg-Gly-Asp) motif, which has high affinity for integrin receptors and is involved in cell adhesion, migration, and other cellular processes. Peptides containing the RGD motif have been extensively studied for their potential applications in targeted drug delivery, molecular imaging, and as therapeutics for conditions such as cancer and angiogenesis-related diseases. |
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R-R-0321 |
Cyclo(-RGDfK) |
Cyclo(-RGDfK)/cas:161552-03-0 is a cyclic peptide sequence containing the RGD motif. Cyclo(-RGDfK) and related cyclic peptides containing the RGD motif have been extensively studied for their potential applications in cancer targeting, tumor imaging, and angiogenesis inhibition. These peptides have shown promise in targeted drug delivery systems, molecular imaging, and as therapeutic agents due to their high affinity for integrin receptors, which are often overexpressed in cancer cells and angiogenic blood vessels. |
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R-R-0322 |
Cyclic(RGDyK) |
Cyclo(RGDyK)/CAS: 250612-42-1 is a selective and potent αVβ3 integrin inhibitor with IC50 value of 20 nM [1]. The αVβ3 integrin, expressed on various malignant human tumors and on endothelial cells, plays an important role in tumor-induced angiogenesis and tumor metastasis. Therefore, αVβ3 integrin is a potential therapeutic target for tumor disease. Inhibition of αVβ3 integrin by αVβ3 antagonists not only blocked blood vessel formation but further led to tumor regression. |
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R-R-0324 |
Cyclo(-RGDfK) TFA |
Cyclo(RGDyK) trifluoroacetate/Cyclo(-RGDfK) TFA/CAS: 500577-51-5/Cyclo(RGDyK) trifluoroacetate refers to a cyclic peptide sequence containing the RGD motif, which has been synthesized in the form of its trifluoroacetate salt. |
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R-R-0372 |
Cyclo(Arg-Gly-Asp-D-Phe-Cys) |
Cyclo(Arg-Gly-Asp-D-Phe-Cys)/CAS.862772-11-0/(Synonyms: Cyclo(RGDfC)), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions.Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors. |
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R-R-0373 |
cyclo (Arg-Gly-Asp-D-Tyr-Cys) |
Cyclo(Arg-Gly-Asp-D-Tyr-Cys) is a cyclic peptide formed by the cyclization of the amino acid sequence Arg-Gly-Asp-D-Tyr-Cys. This cyclic peptide has been studied for its potential biological activities, particularly its ability to bind to integrin receptors, which are involved in cell adhesion and migration. The Arg-Gly-Asp (RGD) sequence is known to interact with integrins, and by cyclizing this sequence along with additional amino acids, it is possible to create a peptide with enhanced stability and potential for use in various biomedical applications, such as in drug development or tissue engineering. As with any peptide, the specific properties and activities of Cyclo(Arg-Gly-Asp-D-Tyr-Cys) would need to be determined through experimental studies. |
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