Catalog name Description price
R-R-0412 Cyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH) sulfoxide Cyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH) sulfoxide/CAS 143120-27-8 from ruixi.This sulfur-bridged cyclic RGD peptide is a potent inhibitor of the binding of glycoprotein IIb/IIIa to fibrinogen with an IC?? of 1.5 nM. Furthermore, it is a highly potent inhibitor of fibrinogen-mediated platelet aggregation (IC?? = 0.15 µM). Its antithrombotic activity in vivo may render this compound useful in the treatment of arterial thromboembolic diseases. price>
R-M-158 Cyclo(-Pro-Tyr),CAS:4549-02-4 The host-specific phytotoxin cyclo(Pro-Tyr),CAS:4549-02-4 produced by Alternaria alternata on spotted knapweed is an ideal prototype for creating a safe and an environmentally friendly antiknapweed herbicide. Furthermore, this cyclic dipeptide induced a high degree of phosphorylation of histones. price>
R-M-159 Cyclo(-Leu-Pro),CAS:2873-36-1 Cyclo(Leu-Pro) showed antibacterial activity. Yan et al. observed that Cyclo(Leu-Pro) produced by Achromobacter xylosoxidans inhibited aflatoxin production by Aspergillus parasiticus. The diketopiperazine was shown to inhibit catecholamine release in vitro. It could play a role in the hypothalamic modulation of appetite suppressant circuitry. Cyclo(L-Leu-L-Pro) is a diketopiperazine metabolite and it has been isolated from various bacterial and fungal species including Streptomyces. It is active against twelve strains of vancomycin-resistant enterococci (VRE) and also inhibits growth of K562, HL-60, and U937 leukemia cells in a concentration-dependent manner when used at concentrations of 1-500 µg/ml. price>
R-M-160 Cyclo(-Leu-Phe),CAS: 7280-77-5 Cyclo(L-phenylalanyl-L-leucyl),Cyclo(-Leu-Phe) is a member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which one hydrogen at position 3 and one hydrogen at position 6 are replaced by benzyl and isobutyl groups (the 3S,6S-diastereomer). It has a role as a metabolite. This diketopiperazine is converted into the antibacterial dehydropeptide albonoursin by cyclo(Leu-Phe) oxidase from S. albulus KO-23. price>
R-M-161 cyclo-GP,CAS :3705-27-9 Cyclo(Gly-Pro) has been detected in rat brain. In the passive avoidance test in rats, synthetic cycloprolylglycine showed 76% antiamnesic activity.Cyclo(Gly-L-Pro) is a cyclodipeptide isolated from the roots of Panax notoginseng (Burk.)F.H.Chen. Cyclo(Gly-L-Pro) was reported to inhibit TNF-α release, IL-1β and IL-6 mRNA expression and NO production. price>
R-M-162 Cyclo(-Leu-Trp),CAS:15136-34-2 The diketopiperazine cyclo(Leu-Trp) has been isolated by Minamiura et al. from casein hydrolyzate by bacterial proteinase. It is one of the bitter compounds detected in cheese. Cyclo(L-Leu-L-Trp) is a diketopiperazine metabolite originally isolated from Penicillium. It is active against various bacteria (MICs = 125-1000 µg/ml) and fungi (MICs = 8-64 µg/ml), and it inhibits the production rate of hydroxy radicals in an electron spin resonance (ESR) spectroscopy-based assay (IC50 = 1.8 µM). Cyclo(L-Leu-L-Trp) is a bitter tastant that can rapidly permeate rat taste cell membranes ex vivo when used at a concentration of 1 mM. It also acts as a melatonin receptor agonist in X. laevis melanophores, inhibiting cAMP accumulation when used at a concentration of 20 µM, an effect that is blocked by the melatonin receptor antagonist luzindole (Cay-15998). price>
R-M-177 C-Peptide (human) trifluoroacetate salt,CAS:33017-11-7 The measurement of the C-peptide under standardized conditions provides a sensitive, well accepted, and clinically validated assessment of b-cell function. The C-peptide measurement is the most suitable primary outcome for clinical trials of therapies aimed at preserving or improving endogenous insulin secretion in type 1 diabetes patients. C-peptide also shows hormonal activity. Clinical studies demonstrated that C-peptide administration in type 1 diabetes patients, who lack the peptide, alleviates the diabetes-induced renal and nerve dysfunctions. price>
R-M-261 Tyr-Proinsulin C-Peptide (55-89) (human),CAS:139532-11-9 Tyr-Proinsulin C-Peptide (55-89) (human),CAS:139532-11-9 from ruixi.Human proinsulin is the precursor of insulin, which is composed of insulin and C-peptide. It has dual immune activity. It can bind with both insulin antibody and C-peptide antibody. Proinsulin is synthesized and secreted by islet beta cells and is mainly metabolized in the kidney. price>
R-M-262 (Tyr⁰)-C-Peptide (human) (Tyr⁰)-C-Peptide (human),CAS : 57327-90-9 from ruixi.C-Peptide derivative for radioimmunoassay. price>
R-M-317 c(RGDyK) c(RGDyK),c(Arg-Gly-Asp-dTyr-Lys) from ruixi.RGD peptide is a peptide containing Arg-Gly-Asp. price>