Product apis-neuronal-signaling

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Catalog	name	Description	price
R-C-2409	Doxazosin CAS: 74191-85-8	Doxazosin(UK 33274)is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.	price>
R-C-2411	Betaxolol CAS:63659-18-7	Betaxolol is a selective beta1 receptor blocker used in the treatment of hypertension and glaucoma.Being selective for beta1+ receptors,it typically has fewer systemic side effects than non-selective beta-blockers,for example,not causing bronchospasm(mediated by beta2 receptors)as timolol may.Betaxolol also shows greater affininty for beta1 receptors than metoprolol.	price>
R-C-2412	Carazolol CAS: 57775-29-8	Carazolol is a beta1/beta2 adrenoceptor antagonist of high potency used in the treatment of hypertension.Its affinity for the beta 3-adrenoceptor was determined in Chinese hamster ovary cells transfected with the gene of the human or the murine beta 3-adrenoceptor.Carazolol is recognized with a nanomolar affinity,which positions it among the best ligands for beta 3-adrenoceptors.	price>
R-C-2413	Metoprolol CAS：51384-51-1	Metoprolol(Toprol)is a selective β1 receptor blocker used in treatment of several diseases of the cardiovascular system,especially hypertension.	price>
R-C-2414	Atenolol CAS：29122-68-7	Atenolol((RS)-Atenolol)is a cardioselective β1-adrenergic receptor blocker,with a Ki of 697nM atβ1-adrenoceptor in guine pig left ventricle membrane.Atenolol can be used for the research of hypertension and angina pectoris.	price>
R-C-2416	Mirabegron CAS： 223673-61-8	Mirabegron(formerly YM-178,trade name Myrbetriq)is a drug for the treatment of overactive bladder.Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder,which leads to muscle relaxation and an increase in bladder capacity.	price>
R-C-2420	Dexmedetomidine CAS:113775-47-6	Dexmedetomidine is notable for its ability to provide sedation without risk of respiratory depression(unlike other commonly used sedatives such as propofol, fentanyl,and midazolam)and can provide cooperative or semi-arousable sedation.	price>
R-C-2421	Pimethixene maleate CAS:13187-06-9	Pimethixene(Pimetixene)maleate,an antihistamine,anntimigraine agent and antiserotonergic compound,is a highly potent antagonist of a broad range of monoamine receptors,including a variety of serotonin receptors.	price>
R-C-2422	Varenicline Hydrochloride CAS:230615-23-3	Varenicline Hydrochloride(CP 526555 hydrochloride)is a high affinity, selective α4β2 nicotine acetylcholine receptor(nAChR)partial agonist and full α7 nAChR agonist.Varenicline Hydrochloride is also a potent partial agonist of α6β2 nAChR in striatum of rats with a Ki value of 0.12nM.	price>
R-C-2423	Myosmine CAS:532-12-7	Myosmine is not only one of the minor tobacco alkaloids but is also present in various foods.Myosmine has low affinity against a4b2 nicotinic acetylcholinergic receptors(nAChR)with Ki of 3300nM.	price>

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