Product supramolecular-chemistry-macrocyclic-ligand

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Catalog	name	Description	price
R-M2-9972	NOTA-PA1	NOTA-PA1 refers to a peptide compound modified with NOTA (1,4,7-triazacyclic nonane-1,4,7-triacetic acid) NOTA-PA1 is mainly used in the field of nuclear medicine imaging, especially in immune checkpoint therapy, for precise detection and monitoring of the expression of DIgVPD-L1 protein. By efficiently chelating radioactive isotopes through NOTA (such as ⁶⁸ Ga for PET imaging and ¹¹¹ In for SPECT imaging), clear imaging of DIgVPD-L1 positive lesions can be achieved.	price>
R-M2-9989	BAPTA-AM,CAS:126150-97-8	BAPTA-AM is a cell-permeable calcium chelator used to regulate intracellular calcium ion (Ca²⁺) concentrations in biological and biochemical research. Once inside cells, cytosolic esterases hydrolyze the AM esters, releasing active BAPTA, which then binds Ca²⁺ions with high selectivity and affinity.	price>
R-M1-8359	Gd-DOTA-N3	Gd-DOTA-N3,Gadolinium-DOTA-azide from ruixibio.Gd-DOTA has various chemical handles for specific modification of biomolecular sites. Gd-DOTA can be used for the development of new protein targeted MRI contrast agents.	price>
R-M1-8365	DOTA-DBCO	DOTA-DBCO can be used as a molecular imaging probe or as a delivery carrier for targeted drugs.Dota is a twelve membered tetraazamacrocyclic ligand.	price>
R-M1c-8381	DOTA-N-(3-aminopropyl)Methacrylamide	DOTA-N-(3-aminopropyl)Methacrylamide,1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-N-(3-aminopropyl)Methacrylamide from ruixibio. DOTA-N-(3-aminopropyl) methylacrylamide, also known as DOTA-AM3, is a bifunctional chelating agent used in the development of radiopharmaceuticals. DOTA stands for 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid, which is a chelating agent that forms stable complexes with various radiometals such as gallium-68, lutetium-177, and others. The addition of an aminopropyl moiety to the DOTA structure allows for conjugation with targeting molecules such as antibodies, peptides, or small molecules, enabling the development of radiopharmaceuticals for targeted imaging or therapy. By forming stable complexes with radiometals, DOTA-AM3 plays a crucial role in the design and development of radiolabeled compounds for applications in nuclear medicine, including positron emission tomography (PET) imaging and targeted radionuclide therapy. We can mass produce (kg level),process scaling up, pilot supply,raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time.	price>
R-M1-8608	Maleimido-mono-amide-DOTA	Maleimido-mono-amide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).	price>
R-M1-8734	DOTA-Laminarin	The conjugation of DOTA with laminarin(DOTA-Laminarin/1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-Laminarin) allows for chelation of radiometals, such as gallium-68 or lutetium-177, making it suitable for imaging or therapeutic applications. DOTA provides stable coordination of the radiometal, while laminarin acts as a carrier and may potentially offer additional biological activities.The DOTA-Laminarin complex may be utilized in various biomedical fields, including molecular imaging, targeted therapy, and drug delivery systems. By combining the chelating properties of DOTA with the natural polysaccharide laminarin, this complex offers potential applications in molecular imaging or theranostics.	price>

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