| Catalog | name | Description | price |
|---|---|---|---|
| R-R-2269 | CHZ868 CAS No.1895895-38-1 | CHZ868/CAS No.1895895-38-1 is a type II JAK2 inhibitor with an IC50 of 0.17 μM in EPOR JAK2 WT Ba/F3 cell. | price> |
| R-R-2270 | JAK2 JH2 Tracer CAS No.2101955-00-2 | JAK2 JH2 Tracer (Tracer 5)/CAS No.2101955-00-2 is a fluorescent probe for JAK2 JH2 domain, with a Kd of value 0.2 μM. | price> |
| R-R-2271 | Baricitinib phosphate CAS No.1187595-84-1 | Baricitinib phosphate (LY3009104 phosphate; INCB028050 phosphate)/CAS No.1187595-84-1 is a selective orally bioavailable JAK1/JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, respectively. | price> |
| R-R-2272 | Atractylenolide I CAS No.73069-13-3 | Atractylenolide I/CAS No.73069-13-3 is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent. | price> |
| R-R-2273 | Zasocitinib CAS No.2272904-53-5 | Zasocitinib (NDI-034858)/CAS No.2272904-53-5 is a TYK2 inhibitor, target TYK2 JH2 domain with binding constant Kd of <200 pM. | price> |
| R-C-574 | SMI-4a cas:327033-36-3 | SIM-4a is a Pim kinase inhibitor that blocks mTORC1 activity via activation of AMPK.Mostly potent to Pim-2,does not significantly inhibit any other serine/threonine-or tyrosine-kinases. | price> |
| R-R-2274 | Delgocitinib CAS No.1263774-59-9 | Delgocitinib (JTE-052)/CAS No.1263774-59-9 is a specific JAK inhibitor with IC50s of 2.8, 2.6, 13 and 58 nM for JAK1, JAK2, JAK3 and Tyk2, respectively. | price> |
| R-R-2275 | Decernotinib CAS No.944842-54-0 | Decernotinib/CAS No.944842-54-0 is a potent, orally active JAK3 inhibitor, with Kis of 2.5, 11, 13 and 11 nM for JAK3, JAK1, JAK2, and TYK2, respectively. | price> |
| R-R-2276 | Oclacitinib maleate CAS No.1640292-55-2 | Oclacitinib maleate (PF-03394197 maleate)/CAS No.1640292-55-2 is a novel JAK inhibitor. Oclacitinib maleate (PF-03394197 maleate) is most potent at inhibiting JAK1 (IC50=10 nM). | price> |
| R-R-2277 | Ruxolitinib (S enantiomer) CAS No.941685-37-6 | Ruxolitinib (S enantiomer) (S-Ruxolitinib)/CAS No.941685-37-6 is the S-enantiomer of Ruxolitinib (HY-50856). Ruxolitinib (S enantiomer) is an orally active, potent JAK inhibitor. | price> |

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