Product apis-apoptosis

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Catalog	name	Description	price
R-R-1682	MN58b CAS No.203192-01-2	MN58b/CAS No.203192-01-2 is a selective choline kinase α (CHKα) inhibitor, and results in inhibition of phosphocholine synthesis. MN58b reduces cell growth through the induction of apoptosis, and also has antitumoral activity.	price>
R-R-1683	SW106065 CAS No.62289-81-0	SW106065/CAS No.62289-81-0 is an apoptosis inducer in malignant peripheral nerve sheath tumors (MPNST). SW106065 inhibits ATP consumption of sMPNST and other models of MPNST with an EC50 of 1 µM. SW106065 can be used for MPNST research.	price>
R-R-1684	Beta-Zearalanol CAS No.42422-68-4	Beta-Zearalenol/CAS No.42422-68-4 is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells. Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid.	price>
R-R-1685	Mps-BAY2a CAS No.1382477-96-4	Mps-BAY2a/CAS No.1382477-96-4 is a monopolar spindle 1 (MPS1) inhibitor with an IC50 of 1 nM against human MPS1. Mps-BAY2a induces mitotic aberrations and apoptosis in cancer cells.	price>
R-R-1686	(E)-Flavokawain A CAS No.37951-13-6	(E)-Flavokawain A/CAS No.37951-13-6, a chalcone extracted from Kava, has anticarcinogenic effect. (E)-Flavokawain A induces apoptosis in bladder cancer cells by involvement of bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice.	price>
R-R-1687	Tauroursodeoxycholate-d5 CAS No.1207294-25-4	Tauroursodeoxycholate-d5/CAS No.1207294-25-4 is the deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.	price>
R-R-1688	Echitamine chloride CAS No.6878-36-0	Echitamine (Ditaine) chloride/CAS No.6878-36-0 is the major monoterpene indole alkaloid present in Alstonia scholaris with potent anti-tumour activity. Echitamine chloride induces DNA fragmentation and cells apoptosis. Echitamine chloride inhibits pancreatic lipase with an IC50 of 10.92 μM.	price>
R-R-1689	Danvatirsen CAS No.1402357-06-5	Danvatirsen/CAS No.1402357-06-5 is an antisense oligonucleotide targeting STAT3 with potential antitumor activity. Danvatirsen binds to STAT3 mRNA, thereby inhibiting translation of the transcript. Suppression of STAT3 expression induces tumor cell apoptosis and decreases tumor cell growth.	price>
R-R-1690	Neocarzinostatin CAS No.9014-02-2	Neocarzinostatin/CAS No.9014-02-2, a potent DNA-damaging, anti-tumor antibiotic, recognizes double-stranded DNA bulge and induces DNA double strand breaks (DSBs). Neocarzinostatin induces apoptosis. Neocarzinostatin has potential for EpCAM-positive cancers treatment.	price>
R-R-1691	QN523 CAS No.878581-60-3	QN523/CAS No.878581-60-3 is a novel scaffold with agent-like properties, showing potent in vitro cytotoxicity in a panel of 12 cancer cell lines. QN523 induces apoptosis and autophagy. QN523 can be used in research of cancer.	price>

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