Product apis-apoptosis

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Catalog	name	Description	price
R-R-1672	Tauroursodeoxycholate-d4 sodium CAS No.2410279-95-5	Tauroursodeoxycholate-d4 (sodium)/CAS No.2410279-95-5 is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.	price>
R-R-1673	Taurochenodeoxycholic acid-d4 sodium CAS No.2410279-85-3	Taurochenodeoxycholic acid-d4 (sodium)/CAS No.2410279-85-3 is the deuterium labeled Taurochenodeoxycholic acid. Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties.	price>
R-R-1674	Xanthoangelol CAS No.62949-76-2	Xanthoangelol/CAS No.62949-76-2, extracted from Angelica keiskei, suppresses obesity-induced inflammatory responses. Xanthoangelol possesses antibacterial activity. Xanthoangelol inhibits monoamine oxidases. Xanthoangelol induces apoptosis in neuroblastoma and leukemia cells.	price>
R-R-1675	Flavokawain A CAS No.3420-72-2	Flavokawain A/CAS No.3420-72-2, a proming anticarcinogenic agent, is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer.	price>
R-R-1676	Soyasapogenol A CAS No.508-01-0	Soyasapogenol A/CAS No.508-01-0, a triterpene compound, isolated from soybean. Soyasapogenol A directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α, which consequently results in the prevention of liver damage in the Concanavalin A-induced hepatitis model.	price>
R-R-1677	OSU-T315 CAS No.2070015-22-2	OSU-T315 (ILK-IN-1)/CAS No.2070015-22-2 is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain). OSU-T315 abrogates AKT activation by impeding AKT localization in lipid rafts and triggers caspase-dependent apoptosis in an ILK-independent manner. OSU-T315 causes cell death through apoptosis and autophagy.	price>
R-R-1678	Hellebrigenin CAS No.465-90-7	Hellebrigenin/CAS No.465-90-7, one of bufadienolides belonging to cardioactive steroids, is isolated from traditional Chinese medicine Venenum Bufonis. Hellebrigenin induces DNA damage and cell cycle G2/M arrest. Hellebrigenin triggers mitochondria-mediated apoptosis.	price>
R-R-1679	MTR-106 CAS No.1639357-93-9	MTR-106/CAS No.1639357-93-9 is a potent and orally active G-quadruplex stabilizer and RNA polymerase I inhibitor. MTR-106 induces apoptosis and inhibits cell growth. MTR-106 can be used in research of cancer.	price>
R-R-1680	Dehydroeffusol CAS No.137319-34-7	Dehydroeffusol/CAS No.137319-34-7 is a phenanthrene from medicinal herb Juncus effuses. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. It shows very low toxicity.	price>
R-R-1681	Tauroursodeoxycholate-d4 CAS No.2410279-94-4	Tauroursodeoxycholate-d4/CAS No.2410279-94-4 is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.	price>

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