Product apis-apoptosis

Home > products > apis> apoptosis

Catalog	name	Description	price
R-R-1568	Lappaol F CAS No.69394-17-8	Lappaol F/CAS No.69394-17-8, a lignin, is an anticancer agent. Lappaol F inhibits YAP<、b> mRNA and protein level. Lappaol F inhibits tumor cell growth by inducing cell cycle arrest. Lappaol F induces cancer cell apoptosis, and inhibits tumor growth. Lappaol F can be isolated from Arctium lappa Linne (Asteraceae).	price>
R-R-1569	Chlorin e6 CAS No.19660-77-6	Chlorin e6/CAS No.19660-77-6 is a photosensitizer and has strong absorption peaks at wavelength of 402 and 662 nm, as well as exhibiting intense fluorescence at 668 nm. Chlorin e6 has antimicrobial efficacy and anticancer activity. Chlorin e6 induces cell apoptosis via caspase-3 activation and can be used for the research of cancer.	price>
R-R-1570	Docetaxel CAS No.114977-28-5	Docetaxel (RP-56976)/CAS No.114977-28-5 is an anti-tumor agent that inhibits microtubule depolymerization with an IC50 value of 0.2 μ M. Docetaxel (RP-56976) weakens the effects of the expression of bcl-2 and bcl-xl genes. Docetaxel (RP-56976) stops the cell cycle and leads to apoptosis in G2/M.	price>
R-R-1571	Trifluridine CAS No.70-00-8	Trifluridine (Trifluorothymidine)/CAS No.70-00-8 is an irreversible and orally active thymidylate synthase inhibitor, and thereby suppressing DNA synthesis. Trifluridine is an antiviral molecule used for research of HSV, rhabdovirus and orthopoxvirus infection. Trifluridine induces cell apoptosis and autophagy. Trifluridine is also an anticancer agent used in studies of metastatic colorectal cancer, gastrointestinal tumors.	price>
R-R-1572	Neriifolin CAS No.466-07-9	Neriifolin/CAS No.466-07-9, a CNS-penetrating cardiac glycoside, is an inhibitor of the Na+, K+-ATPase. Neriifolin can target beclin 1, inhibits the formation of LC3-associated phagosomes and ameliorates experimental autoimmune encephalomyelitis (EAE) development. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.	price>
R-R-1573	Azilsartan CAS No.147403-03-0	Azilsartan (TAK-536)/CAS No.147403-03-0 is an orally active, potent, selective and specific angiotensin II type 1 receptor (AT1) antagonist. Azilsartan induces ROS formation and apoptosis in HepG2 cells. Azilsartan shows neuroprotective and anticancer activity. Azilsartan can be used for hypertension and stroke research.	price>
R-R-1574	Alrizomadlin CAS No.1818393-16-6	Alrizomadlin (APG-115)/CAS No.1818393-16-6 is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner.	price>
R-R-1576	Taurodeoxycholic acid CAS No.516-50-7	Taurodeoxycholic acid/CAS No.516-50-7, a bile acid, stabilizes the mitochondrial membrane, decreases free radical formation. Taurodeoxycholic acid inhibits apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation.	price>
R-R-1577	Piclidenoson CAS No.152918-18-8	Piclidenoson (IB-MECA)/CAS No.152918-18-8 is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist. Piclidenoson exhibits antiproliferative effect and induces apoptosis in different cancer cell types like melanoma, leukemia. Piclidenoson can be used for the research of autoimmune inflammatory diseases and COVID-19.	price>
R-R-1578	Citreoviridin CAS No.25425-12-1	Citreoviridin/CAS No.25425-12-1, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-dependent manner. Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells.	price>

...