Catalog |
name |
Description |
price |
R-M-5477 |
MB 594 DBCO |
MB™594 is a very hydrophilic, water-soluble red fluorescent dye.Characteristic features of MB™594 are strong absorption, high fluorescence quantum yield, high photostability, and pH insensitivity from pH 3 to pH 10. MB™594 is a highly suitable dye for single-molecule detection applications and high-resolution microscopy such as PALM, dSTORM, STED etc.MB 594 DBCO reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. In application where the presence of copper is a concern MB™ 594 DBCO is an ideal alternative to copper requiring fluorescent alkynes. |
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R-M-5478 |
MB 594 Maleimide |
MB™594 is a very hydrophilic, water-soluble red fluorescent dye.Characteristic features of MB™ 594 are strong absorption, high fluorescence quantum yield, high photostability, and pH insensitivity from pH 3 to pH 10. MB™594 is a highly suitable dye for single-molecule detection applications and high-resolution microscopy such as PALM, dSTORM,STED etc.Maleimide is the most popular sulfhydryl-reactive reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups,–SH) at pH 6.5 to 7.5 to form stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores. |
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R-M-5479 |
MB 633 NHS Ester |
MB 633 NHS Ester from ruixi.MB 633 is a novel, rhodamine-based dye with its absorption peak at 630 nm. MB 633 can be optimally excited by the 633 nm He-Ne laser or the 635 nm red diode laser with emission maximum at 650 nm. The most important advantage of MB 633 and other rhodamine-based far-red MB dyes are their unmatched photostability. The combination of superior brightness and photostability makes far-red MB dyes ideal choices for detection in the long wavelength region on a variety of instruments. |
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R-M-5480 |
MB 660R Acid |
MB™660R is a bright and photostable far-red dye that emits fluorescence at about 685 nm in the borderline spectral region between far-red and near-IR. Although the absorption maximum is at around 665 nm, this dye can be sufficiently excited by the 633 or 635 nm laser. MB™660R dye is water soluble and pH-insensitive from pH 4 to pH 10. MB 660R is a rhodamine-based dye, and like rhodamine dyes in general, it is exceptionally photostable. The superior photostability and excellent brightness of MB 660R make the dye an ideal choice for confocal microscopy and other demanding applications.MB™660R Acid often used for the preparation of custom activated esters. |
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R-M-5481 |
MB 660R NHS Ester |
MB™660R is a bright and photostable far-red dye that emits fluorescence at about 685 nm in the borderline spectral region between far-red and near-IR. Although the absorption maximum is at around 665 nm, this dye can be sufficiently excited by the 633 or 635 nm laser. MB™660R dye is water soluble and pH-insensitive from pH 4 to pH 10. MB 660R is a rhodamine-based dye, and like rhodamine dyes in general, it is exceptionally photostable (Figure 1, description tab). The superior photostability and excellent brightness of MB 660R make the dye an ideal choice for confocal microscopy and other demanding applications.The NHS Ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a stable, covalent amide bond. The NHS ester (or succinimidyl ester) is the most popular tool for conjugating dyes to the primary amines of protein or antibody (Lys), amine-modified oligonucleotides, and other amine-containing molecules. |
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R-M-5482 |
MB 660R TFP Ester |
MB™ 660R is a bright and photostable far-red dye that emits fluorescence at about 685 nm in the borderline spectral region between far-red and near-IR. Although the absorption maximum is at around 665 nm, this dye can be sufficiently excited by the 633 or 635 nm laser. MB™ 660R dye is water soluble and pH-insensitive from pH 4 to pH 10. MB 660R is a rhodamine-based dye, and like rhodamine dyes in general, it is exceptionally photostable (Figure 1, description tab). The superior photostability and excellent brightness of MB 660R make the dye an ideal choice for confocal microscopy and other demanding applications.TFP (tetrafluorophenyl) ester is an amine-reactive activated ester that reacts with primary amines of biomolecules in the same way as the succinimidyl ester (SE or NHS-ester) to form a stable amide bond. The major advantage of TFP esters over the succinimidyl ester is better resistance to spontaneous hydrolysis during conjugation reactions, which results in more efficient and reproducible labeling of biopolymers. TFP esters are stable for several hours at the basic pH typically used for reactions–far outlasting succinimidyl esters. |
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R-M-5483 |
MB 680R TFP Ester |
MB™ 680R is a bright and photostable far-red dye that emits fluorescence at about 685 nm in the borderline spectral region between far-red and near-IR. Although the absorption maximum is at around 680 nm, this dye can be sufficiently excited by the 633 or 635 nm laser. MB™ 680R dye is water soluble and pH-insensitive from pH 4 to pH 10. MB 680R is a rhodamine-based dye, and like rhodamine dyes in general, it is exceptionally photostable. The superior photostability and excellent brightness of MB 680R make the dye an ideal choice for confocal microscopy and other demanding applications.TFP (tetrafluorophenyl) ester is an amine-reactive activated ester that reacts with primary amines of biomolecules in the same way as the succinimidyl ester (SE or NHS-ester) to form a stable amide bond. The major advantage of TFP esters over the succinimidyl ester is better resistance to spontaneous hydrolysis during conjugation reactions, which results in more efficient and reproducible labeling of biopolymers. TFP esters are stable for several hours at the basic pH typically used for reactions–far outlasting succinimidyl esters. |
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R-M-5484 |
MB 680R NHS Ester |
MB™ 680R is a bright and photostable far-red dye that emits fluorescence at about 685 nm in the borderline spectral region between far-red and near-IR. Although the absorption maximum is at around 680 nm, this dye can be sufficiently excited by the 633 or 635 nm laser. MB™ 680R dye is water soluble and pH-insensitive from pH 4 to pH 10. MB 680R is a rhodamine-based dye, and like rhodamine dyes in general, it is exceptionally photostable. The superior photostability and excellent brightness of MB 680R make the dye an ideal choice for confocal microscopy and other demanding applications.The NHS Ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a stable, covalent amide bond. The NHS ester (or succinimidyl ester) is the most popular tool for conjugating dyes to the primary amines of protein or antibody (Lys), amine-modified oligonucleotides, and other amine-containing molecules. |
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R-M-5485 |
MB 800Z NHS ester |
MB 800Z NHS ester from ruixi.MB 800Z is a conceptually new class of sterically shielded NIR cyanine heptamethine dye. This dye contains two shielding PEG arms directly over both faces of the heptamethine fluorochrome blocking any undesired bimolecular association processes and thus dramatically enhances the fluorescence brightness. A recently published antibody labeling study clearly demonstrated 1-2 order of magnitude increase in brightness compared to commercially available NIR dyes as a result of almost complete prevention of stacking of multiple fluorophores appended to the antibody surface.MB 800Z is a zwiteroinic, charge-balanced dye with an equal number of anionic sulfonate and cationic ammonium residues, a structural feature that is known to reduce interactions with off -target biological surfaces. MB 800Z will enable researchers to greatly improve various types of indirect NIR immunofluorescence imaging and diagnostics applications that require high sensitivity and also develop new photonintense techniques that require high photostability. |
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