Catalog |
name |
Description |
price |
R-C-1885 |
Saquinavir mesylate CAS:149845-06-7 |
Saquinavir mesylate is an HIV Protease Inhibitor used in antiretroviral therapy. |
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R-C-1905 |
BAG956 CAS:853910-02-8 |
BAG 956,also known as NVP-BAG956,is a dual PDK1 and class I PI 3-kinase inhibitor.BAG 956 has been shown to inhibit cellular AKT phosphorylation at Thr308.BAG 956 also blocks cell proliferation and causes arrest in the G1 phase of the cell cycle.BAG 956 has been shown to slow tumor progression in mouse xenograft models. |
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R-C-1907 |
ARN-3236 CAS:1613710-01-2 |
ARN-3236 is potent,orally active and selective SIK2 inhibitor.ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6μmol/L. |
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R-C-1915 |
DWK-1339 CAS:1018946-38-7 |
MDR-1339(DWK-1339)is an orally active and blood-brain-barrier-permeable Aβ-aggregation inhibitor,used in the research of Alzheimer is disease. |
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R-C-1927 |
Cilofexor (GS-9674) CAS:1418274-28-8 |
Cilofexor(GS-9674)is a potent,selective and orally active nonsteroidal FXR agonist with an EC50 of 43nM.Cilofexor has anti-inflammatory and antifibrotic effects.Cilofexor has the potential for primary sclerosing cholangitis(PSC)and nonalcoholic steatohepatitis(NASH)research. |
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R-C-1937 |
S119-8 CAS:443639-96-1 |
S119-8 is a broad spectrum inhibitor of influenza A and B viruses,showing activity against multiple influenza B viruses and an oseltamivir-resistant influenza A virus,but does not inhibit a non-influenza virus,vesicular stomatitis nirus(VSV). |
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R-C-1938 |
NAV-2729 CAS: 419547-11-8 |
NAV-2729 is a selective ARF6 inhibitor(IC50=1.0μM).Blocking ARF6 with a small-molecule inhibitor reduces uveal melanoma cell proliferation and tumorigenesis in a mouse model,confirming the functional relevance of this pathway and suggesting a therapeutic strategy for Gα-mediated diseases. |
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R-C-1939 |
INF-39 CAS:866028-26-4 |
INF39 is a nontoxic,irreversible NLRP3 inhibitor that counteracts NLRP3 activation through direct irreversible interaction with NLRP3 and partial inhibition of LPS-driven pro-inflammatory gene expression. |
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R-C-1940 |
FTBMT CAS:1358575-02-6 |
FTBMT is a selective GPR52 agonist.It demonstrates antipsychotic-like and procognitive effects in rodents and has revealed a potential therapeutic agent for schizophrenia. |
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R-C-1943 |
PU-WS13 CAS:1454619-14-7 |
PU-WS13 is a potent,Grp94-specific Hsp90 inhibitor of the purine scaffold class. PU-WS13 is a cell-permeable inhibitor of Grp94 with EC50 of 220 nM. |
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