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R-Mcs-184 DOTAP:DOPC:Chol:DPPE-N-(6-azidohexanoyl)-Rhodamine lipid (headgroup)-Azide DOTAP:DOPC:Chol:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(6-azidohexanoyl) (ammonium salt){5:64:30:1molar ratio}-based Fluoroliposome Rhodamine lipid (headgroup)-Azide is a DOTAP-based Fluoroliposome-Azide for Tracking,Drug Delivery,Imaging Studies,Targeted Therapy and Diagnostics and Detection. price>
R-XASYS-00185 Camalexin,cas:135531-86-1 Camalexin is a phytoalexin isolated from Camelina sativa (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production price>
R-R-0185 CY5-chloramphenicol CY5-chloramphenicol/Cyanine5-chloramphenicol refers to a conjugate of the antibiotic drug chloramphenicol with the fluorescent dye CY5. Chloramphenicol is a broad-spectrum antibiotic commonly used in the treatment of various bacterial infections.The conjugation of CY5 with chloramphenicol allows for the visualization and tracking of the antibiotic within biological systems using fluorescence techniques. This can be valuable in studying the distribution, uptake, and efficacy of chloramphenicol in bacterial or cellular systems. price>
R-Mcs-185 DOTAP:DOPC:Chol:DPPE-N-(6-azidohexanoyl) (ammonium salt)-Cyanine 5 lipid-Azide DOTAP:DOPC:Chol:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(6-azidohexanoyl) (ammonium salt){5:64:30:1molar ratio}-based Fluoroliposome Cyanine 5 lipid-Azide can promote its safe and effective delivery to target cells. The presence of cationic DOTAP may facilitate the delivery of genetic material (DNA/RNA) into cells, making it a candidate for gene therapy applications. Due to the Cy5 tag, these liposomes can be used in fluorescence imaging to track cellular uptake and behavior of the liposomal payload in real time. The azide moiety allows for specific labeling or modification of the liposomes, enabling a wide range of biochemical applications, including the attachment of targeting ligands or other functional components. price>
R-XASYS-00186 L67,cas:325970-71-6 L67 (DNA Ligase Inhibitor) is a competitive DNA ligase inhibitor that effectively inhibits DNA ligases I/III (both IC50 are 10 μM). L67 (DNA Ligase Inhibitor) can cause nuclear DNA damage by reducing levels of mitochondrial DNA and increasing levels of mitochondrially-generated ROS. price>
R-R-0186 FITC-palmitic acid FITC-palmitic acid/Fluorescein-palmitic acid refers to the conjugate of the fluorescent dye FITC (fluorescein isothiocyanate) with palmitic acid, a long-chain saturated fatty acid.FITC-palmitic acid can be used in a variety of experiments to study lipid metabolism, membrane dynamics, lipid-protein interactions, and other related processes. Its fluorescent properties allow for visualization and detection, providing insights into the behavior and role of palmitic acid within biological systems. price>
R-Mcs-186 DOTAP:DOPC:Chol:DPPE-N-(6-azidohexanoyl) (ammonium salt)-Cyanine 5.5 lipid-Azide DOTAP:DOPC:Chol:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(6-azidohexanoyl) (ammonium salt){5:64:30:1molar ratio}-based Fluoroliposome Cyanine 5.5 lipid-Azide is a DOTAP-based Fluoroliposome-Azide for Tracking,Drug Delivery,Imaging Studies,Targeted Therapy and Diagnostics and Detection. The cationic nature of DOTAP allows for effective encapsulation and delivery of nucleic acids, making these liposomes suitable for gene therapy or RNA-based therapies. The liposomes can encapsulate small molecule drugs, providing a means for targeted delivery to cells, which could lower systemic toxicity and improve therapeutic efficacy. Cy5.5 allows researchers to trace and visualize the distribution and uptake of the liposomes in cells or tissues using fluorescence techniques. The azide group serves as a versatile handle for attaching various targeting ligands (like antibodies or peptides) or imaging agents, enhancing the specificity and functionality of the liposomes. price>
R-XASYS-00187 W-54011,cas:405098-33-1 W-54011 is a potent and orally active non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils with a Ki value of 2.2 nM price>
R-R-0187 CY5-heparin sulfate CY5-heparin sulfate/Cyanine5-heparin sulfate is a conjugate of the fluorescent dye CY5 with heparin sulfate, a complex polysaccharide. CY5-heparin sulfate can be utilized in various research applications, including fluorescence imaging of heparan sulfate proteoglycans, tracking cellular uptake and intracellular trafficking of heparin sulfate, investigating heparin sulfate interactions with proteins or cells, and studying heparin sulfate-based drug delivery systems. price>
R-Mcs-187 DOTAP:DOPC:Chol:DPPE-N-(6-azidohexanoyl) (ammonium salt)-Cyanine 7 lipid-Azide DOTAP:DOPC:Chol:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(6-azidohexanoyl) (ammonium salt){5:64:30:1molar ratio}-based Fluoroliposome Cyanine 7 lipid-Azide is a DOTAP-based Fluoroliposome-Azide for Tracking,Drug Delivery,Imaging Studies,Targeted Therapy and Diagnostics and Detection. price>
R-XASYS-00188 Daphnetin,cas:486-35-1 Daphnetin (7,8-dihydroxycoumarin) is a coumarin derivative that can be derived from Genus Daphne and is an orally effective protein kinase inhibitor with an IC50 value of 7.67 for EGFR, PKA, and PKC, respectively μ M、9.33 μ M and 25.01 μ M。 Daphnetin triggers reactive oxygen species induced apoptosis and induces cytoprotective autophagy by regulating the AMPK/Akt/mTOR pathway. price>
R-R-0188 FITC-T7 peptide FITC-T7 peptide/Fluorescein-T7 peptide refers to a conjugate of the fluorescent dye FITC (fluorescein isothiocyanate) with the T7 peptide sequence. FITC-T7 peptide has various applications in biomedical research, particularly in studying T7 RNA polymerase interactions, protein-protein interactions mediated by the T7 peptide sequence, and investigating the expression and localization of T7-tagged proteins within cells or tissues. Its fluorescent properties allow for easy detection and visualization, aiding in the understanding of biological processes and molecular interactions involving the T7 peptide. price>
R-Mcs-188 DOTAP:DOPC:Chol:DSPE-DBCO(5:64:30:1molar ratio)-based Fluoroliposome DiA-DBCO DOTAP:DOPC:Chol:DSPE-DBCO(5:64:30:1molar ratio)-based Fluoroliposome DiA-DBCO for a variety of biomedical applications, including targeted treatment and diagnostic imaging. The cationic nature of DOTAP aids in the delivery of nucleic acids and therapeutic agents, enhancing their uptake by cells. Fluoroliposomes can be used as imaging agents due to their ability to encapsulate fluorescent dyes, allowing for visual tracking of liposomes in biological systems. With the presence of DBCO, the liposomes can be modified further post-formation, allowing for attachment of other molecules such as antibodies or fluorescent markers through click chemistry. price>
R-XASYS-00189 Urolithin C,cas:165393-06-6 Urolithin C, a polyphenolic intestinal microbial metabolite of ellagic acid, is a glucose dependent activator of insulin secretion. Urolithin C is an L-type Ca2+channel opener that enhances Ca2+influx. Urolithin C induces apoptosis and stimulates the formation of reactive oxygen species (ROS) through mitochondrial mediated pathways price>
R-Mcs-189 DOTAP:DOPC:Chol:DSPE-N-DBCO(5:64:30:1molar ratio)-based Fluoroliposome DiD-DBCO This DOTAP:DOPC:Chol:DSPE-DBCO-based fluoro-liposome formulation encapsulating DiD provides a robust platform for various biomedical applications, especially in drug delivery and imaging. The encapsulation of DiD allows researchers to visualize the distribution and localization of the liposomes in biological systems, which can be critical for tracking drug delivery and understanding biodistribution. The reactive DSPE-DBCO allows for post-formation conjugation with targeting ligands (e.g., antibodies or peptides), potentially directing the liposomes to specific cell types or tissues. The cationic nature of DOTAP can be beneficial in delivering nucleic acids, such as plasmid DNA or RNA, enhancing transfection efficiency. price>
R-R-0189 Azidoethyl-SS-propionic NHS ester CAS: 2243566-44-9 Azidoethyl-SS-propionic NHS ester CAS:2243566-44-9 is a chemical compound that contains three functional groups: an azide group, an ester group, and an N-hydroxysuccinimide (NHS) ester group. The azide group allows for bioorthogonal chemistry, which enables selective labeling and detection of biological molecules. The ester group is often used for covalent bonding to amine-containing molecules, while the NHS ester group is commonly used for protein and antibody labeling. Together, these functional groups make Azidoethyl-SS-propionic NHS ester a useful reagent for a wide range of biochemical and biomedical applications. price>
R-XASYS-00190 Garcinone D,cas:107390-08-9 Garcinone D is a natural xanthone from bamboo, which can promote the proliferation of C17.2 neural stem cells. Garcinone D increases phosphorylation signal transducer and transcriptional activator 3 (p-STAT3), Cyclin D1, and nuclear factor erythrocyte 2 related factor (Nrf2), and heme oxygenase-1 (HO-1) protein levels in a concentration and time dependent manner. price>
R-R-0190 Adamantane-luminol Adamantane-luminol is a conjugate formed by attaching the molecule adamantane to luminol. Adamantane is a rigid, cage-like hydrocarbon structure, while luminol is a chemiluminescent compound commonly used in analytical chemistry and forensic science.By conjugating adamantane to luminol, new applications can be explored. The adamantane-luminol conjugate can potentially be used as a probe or marker in various biological assays. For example, it can be used for the detection and quantification of specific analytes in biological samples, such as reactive oxygen species (ROS) or certain enzymes. price>
R-Mcs-190 DOTAP:DOPC:Chol:DSPE-N-DBCO(5:64:30:1molar ratio)-based Fluoroliposome DiI-DBCO The DOTAP:DOPC:Chol:DSPE-DBCO fluoroliposome with DiI is a sophisticated system designed for targeted drug delivery, imaging, and biochemical applications. The combination of a cationic lipid for cell interaction, a neutral lipid for bilayer stability, cholesterol for membrane integrity, a bioorthogonal linker for functionalization, and a fluorescent dye for tracking makes this formulation versatile for various research and therapeutic applications. price>
R-XASYS-00191 Aurothioglucose,cas:12192-57-3 Aurothiolucose (Gold thiolucose) contains monovalent gold ions and is an effective inhibitor of the active site of TrxR1 (thioredoxin reductase 1) with an IC50 of 65 nM. Aurothioglucose inhibits NF in vitro- κ DNA binding of B. Aurothioglucose has anti HIV and anti rheumatic activities. price>