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Catalog	name	Description	price
R-R-5664	Gilteritinib (ASP2215) Liposomes CAS No.1254053-43-4	Gilteritinib (ASP2215)/CAS No.1254053-43-4 is a small-molecule inhibitor of FLT3/AXL with IC50 values of 0.29 nM and 0.73 nM for FLT3 and AXL, respectively. Gilteritinib (ASP2215) is a highly selective FLT3 inhibitor that demonstrates activity against both FLT3-ITD and FLT3-TKD mutation subtypes and selectively inhibits FLT3 at concentrations roughly 800-fold lower than those required to inhibit c-Kit (230 nM). This product is a pre-formulated liposomal version of Gilteritinib (ASP2215) which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance; the lipid composition of the liposomes is the same as Doxil. For preclinical research use only.	price>
R-M-1539	(Gly106)-Cytochrome C (92-107) (Manduca sexta),CAS :213260-63-0	This peptide is an antigenic peptide that prevents the development of mature 2B4 TCRhi CD4+8+ thymocytes, competitively blocks antigen induced IL-2 production plays major role in T-cell selection.	price>
R-C-3985	DSPE-PEG350-sucrose	DSPE-PEG is a PEG-modified lipids.so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups.Sucrose,organic compound,molecular weight 342.3.Colorless crystal,with optical rotation,but no variable rotation.	price>
R-R-5665	HSPC/Chol/DSPE-mPEG2000/DSPE-mPEG2000-maleimide (50/45/4/1, mol/mol) Liposomes	HSPC/Chol/DSPE-mPEG2000/DSPE-mPEG2000-maleimide (50/45/4/1, mol/mol) Liposomes. PEGylated liposomes containing free maleimide functional group for maleimide-thiol conjugation. The liposomes are co-formulated with 1 mol% DSPE-mPEG2000-maleimide, and supplied in a pH-optimized buffer for direct conjugation of the thiol-containing molecule of choice. Conjugation can be achieved by incubating the liposomes with the activated thiol-containing compound which has been reduced by a disulfide bond reducing agent such as (tris(2-carboxyethyl)phosphine) (TCEP), which can be purchased as an add-on.	price>
R-M-1540	(Trp63,Trp64)-C3a (63-77),CAS:130154-64-2	(Trp63,Trp64)-C3a (63-77), synthetic superagonist analog of complement 3a, was 12-15 times more active than natural C3a.	price>
R-C-3986	DSPE-polyethylene glycol550-sucrose	DSPE-PEG is a PEG-modified lipids.so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups.Sucrose,organic compound,molecular weight 342.3.Colorless crystal,with optical rotation,but no variable rotation.	price>
R-R-5666	Tanespimycin (17-AAG) Liposomes, Formulation XT28.1	Tanespimycin (17-AAG) Liposomes, Formulation XT28.1. PEGylated liposomes containing Hsp90 inhibitor Tanespimycin (17-AAG). Tanespimycin exhibits 100-fold higher binding affinity to HSP90 derived from tumor cells vs normal cells, and induces apoptosis, necrosis, autophagy, and mitophagy. Tanespimycin is insoluble in aqueous media. This product is a pre-formulated liposomal version of Tanespimycin which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only.	price>
R-M-1541	[Ala9] Autocamtide 2,CAS:167114-91-2	Highly specific and potent inhibitor of calmodulin-dependent protein Kinase II (IC50= 40 nM) that does not affect cycle AMP-dependent protein kinase, protein kinase C and calmodulin-dependent protein kinase IV.	price>
R-C-3987	sucrose-PEG750-DSPE	DSPE-PEG is a PEG-modified lipids.so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups.Sucrose,organic compound,molecular weight 342.3.Colorless crystal,with optical rotation,but no variable rotation.	price>
R-R-5667	DT-061 (SMAP) Liposomes, Formulation TT-40	DT-061 (SMAP) Liposomes, Formulation TT-40. PEGylated liposomes containing PP2A activator DT-061 (SMAP). DT-061 is an activator of protein phosphatase 2A (PP2A). PP2A regulates many cellular signaling pathways including MAPK/ERK, Wnt/β-catenin, Akt/mTOR, GSK3β, p53/apoptosis, cell cycle, and others. This product can be used in vitro or in vivo for studying the effects of PP2A activation and could be applied to preclinical therapy of KRAS-mutant and MYC-driven tumors. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only.	price>
R-M-1545	Acetyl-ccβ	The ccβ peptide has been used to study conformational changes in response to stimuli such as temperature and salt. The ccβ peptide adopts a three-stranded alpha-helical coiled-coil structure at low temperature and changes to an amyloid conformation with increasing temperature. The ccβ peptide can be used as a model for prion diseases and in amyloid studies.	price>
R-C-3988	DSPE-PEG350-L-valine	Valine is one of the 20 amino acids that make up proteins.Its chemical name is 2-amino-3-methylbutyric acid.It works with two other high concentration amino acids(isoleucine and leucine)to promote normal body growth,repair tissues, regulate blood glucose and provide required energy.DSPE-PEG is a PEG-modified lipids.so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups.	price>
R-R-5668	Liposomes for Loading Hydrophobic Drugs	Liposomes for Loading Hydrophobic Drugs (5.0mL). This pre-formed liposome product is created for post loading of hydrophobic small molecule compounds into liposomes. The process of drug incorporation is very straight-forward. Then simply add an aliquot of drug solution (prepared in a water-miscible solvent such as ethanol, DMSO and etc.) into the liposome suspension. The drug molecules can be incorporated into the lipid bilayers by the nature of hydrophobic interactions. The drug solubility therefore could be significantly enhanced. Liposomal drug concentration of 1-2 mg/mL could be achieved for most lipophilic drugs. PEGylation of the liposomes provides not only better formulation stability but also the potential of achieving prolonged in vivo blood circulation. The finished drug loaded formulations are suitable for either in vitro testing or in vivo studies.	price>
R-M-1548	Beta-Amyloid (12-20),CAS :134649-29-9	β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Amino acids 12-20 of the amyloid beta peptide, a key subunit of extracellular plaques found in the brains of patients with Alzheimer’s disease.	price>
R-R-5669	HSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm)	HSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm). HSPC/CHO liposomes with ammonium gradient is the formulator choice for loading of weakly basic compounds, because it offers significantly improved drug retention and the ease of use in terms of process parameters such as loading temperature (60-70 deg C). One can use this liposomes as the placebo control for the drug loaded formulation or use the much cheaper plain HSPC/CHOL liposomes as placebo control.	price>
R-M-1549	Biotin-β Amyloid (1-42) Human,Cas:102577-21-9	Amino acids 1-42 of amyloid beta protein, a key subunit of extracellular plaques found in the brains of patients with Alzheimer’s disease. Contains covalently attached N-Terminal Biotin tag for con-venient detection and purification.	price>
R-C-3990	DSPE-polyethylene glycol550-L-valine	Valine is one of the 20 amino acids that make up proteins.Its chemical name is 2-amino-3-methylbutyric acid.It works with two other high concentration amino acids(isoleucine and leucine)to promote normal body growth,repair tissues, regulate blood glucose and provide required energy.DSPE-PEG is a PEG-modified lipids.so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups.	price>
R-R-5670	DSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm)	DSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm). DSPC/CHO liposomes with ammonium gradient is the formulator choice for loading of weakly basic compounds, because it offers significantly improved drug retention and the ease of use in terms of process parameters such as loading temperature (60-70 deg C). One can use this liposomes as the placebo control for the drug loaded formulation or use the much cheaper plain DSPC liposomes as placebo control (F10203).	price>
R-M-1551	Pyroglutamyl β-Amyloid (4-14) Biotin	Pyroglutamyl β-Amyloid (4-14) Biotin is derived from Amyloid-β, which has been identified as the key subunit of the extracellular plaques found in the brains of patients with Alzheimer’s disease (AD) and Down’s syndrome (DS).	price>
R-C-3991	valine-L-PEG750-DSPE	Valine is one of the 20 amino acids that make up proteins.Its chemical name is 2-amino-3-methylbutyric acid.It works with two other high concentration amino acids(isoleucine and leucine)to promote normal body growth,repair tissues, regulate blood glucose and provide required energy.DSPE-PEG is a PEG-modified lipids.so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups.	price>

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