Home > Keywords >
Catalog | name | Description | price |
---|---|---|---|
R-R-4681 | N-Acetyl-Calicheamicin CAS No.108212-76-6 | N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ)/CAS No.108212-76-6, an enediyne anti-tumor antibiotic, is an ADC cytotoxin. N-Acetyl-Calicheamicin can induce DNA damage, and can be used in the synthesis of ADC. | price> |
R-C-2982 | LED209 CAS:245342-14-7 | Led209 is an effective small molecule inhibitor of bacterial receptor qseC. It is an effective prodrug with high selectivity for qseC. Only for scientific research, not for human body. | price> |
R-C-3012 | WUN-29654 (CRBN modulator-1) CAS:2407829-65-4 | WUN-29654 (CRBN modulator-1, compound 10) is a Thalidomide analog and a CRBN modulator with IC50 of 3.5 μM and Ki of 0.98 μM for CRBN binding. | price> |
R-R-4682 | Garenoxacin Mesylate hydrate CAS No.223652-90-2 | Garenoxacin (BMS284756) Mesylate hydrate/CAS No.223652-90-2 is an orally active quinolone antibiotic and has a broad spectrum of activity against a wide array of gram-positive and gram-negative bacteria, anaerobes, and fastidious organisms. | price> |
R-C-2983 | Ro 64-5229 CAS: 139339-45-0 | Ro24-7429 is an effective and orally active HIV-1 transactivator Tat antagonist. Ro24-7429 is also a Runx1 inhibitor. Only for scientific research, not for human body. | price> |
R-C-3013 | ML-385 CAS:846557-71-9 | ML385 inihbits the activity of the Nrf2 transcription factor by binding to Neh1, a CNC-bZIP domain that allows Nrf2 to heterodimerize with small Maf proteins, blocking NRF2 transcriptional activity. Only for scientific research, not for human body. | price> |
R-R-4683 | Netropsin dihydrochloride CAS No.18133-22-7 | Netropsin dihydrochloride/CAS No.18133-22-7 is a small-molecule MGB (minor-groove binder), inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei. Netropsin dihydrochloride exhibits antiviral activity against the vaccinia virus. | price> |
R-C-3014 | SB525334 CAS:356559-20-1 | SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM in a cell-free assay, 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.Only for scientific research, not for human body. | price> |
R-R-4684 | Adenine-13C CAS No.86967-48-8 | Adenine-13C/CAS No.86967-48-8 is the 13C labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis. | price> |
R-C-3015 | Frentizole CAS:26130-02-9 | Frentizole (Frentizol) is a novel inhibitor of amyloid beta peptide (Abeta) binding alcohol dehydrogenase (ABAD) interaction with IC50 of 200 μM. Only for scientific research, not for human body. | price> |
R-R-4685 | Tezacitabine CAS No.130306-02-4 | Tezacitabine/CAS No.130306-02-4 is a cytostatic and cytotoxic antimetabolite and a nucleoside analogue. Tezacitabine irreversibly inhibits the ribonucleotide reductase and interferes with DNA replication and repair. Tezacitabine effectively induces cells apoptotic. Tezacitabine has the potential for leukemias and solid tumors (carcinomas) treatment. | price> |
R-C-3016 | NU7441 (KU-57788) CAS:503468-95-9 | NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits mTOR and PI3K with IC50 of 1.7 μM and 5 μM in cell-free assays, respectively. It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage.Only for scientific research, not for human body. | price> |
R-R-4686 | AV-153 free base CAS No.19350-66-4 | AV-153 free base/CAS No.19350-66-4, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity. | price> |
R-C-3017 | SB269970 HCl CAS:261901-57-9 | SB269970 hydrochloride (SB-269970A) is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with the pKi of 8.3, exhibits >50-fold selectivity against other receptors.Only for scientific research, not for human body. | price> |
R-R-4687 | DTP3 TFA CAS No.2759216-46-9 | DTP3 TFA/CAS No.2759216-46-9 is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway. | price> |
R-R-4688 | H3B-968 CAS No.2912294-90-5 | H3B-968/CAS No.2912294-90-5 is a potent inhibitor of Werner syndrome protein (WRN) (IC50=~10 nM),which acts function as helicase,ATPase,and exonuclease. WRN exhibits synthetic lethal activity in cancer research. However,H3B-968 inhibits WRN helicase activity,competitively with ATP. | price> |
R-R-4689 | Pseudouridimycin CAS No.1566586-52-4 | Pseudouridimycin (PUM)/CAS No.1566586-52-4, an antibiotic, is a selective bacterial RNA polymerase (RNAP) inhibitor. Pseudouridimycin is a C-nucleoside analogue that is effective against both Gram-negative and Gram-positive bacteria. | price> |
R-R-4690 | 6-Hydroxy-DOPA CAS No.21373-30-8 | 6-Hydroxy-DOPA/CAS No.21373-30-8 is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer. | price> |
R-R-4691 | 5-Propargylamino-dCTP CAS No.115899-39-3 | 5-Propargylamino-dCTP/CAS No.115899-39-3 is a nucleoside molecule extracted from patent US9035035B2, compound dCTP-PA. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis. 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | price> |
R-R-4692 | (2,2-Bipyridine)bis[2-(2,4-difluorophenyl)pyridine]iridium(III) Hexafluorophosphate CAS :864163-80-4 | (2,2-Bipyridine)bis[2-(2,4-difluorophenyl)pyridine]iridium(III) Hexafluorophosphate/CAS :864163-80-4 is a coordination complex featuring an iridium(III) ion at its core. The complex is comprised of 2,2-bipyridine ligands and two 2-(2,4-difluorophenyl)pyridine ligands that coordinate with the iridium ion. The hexafluorophosphate anion (PF₆⁻) is included in the compound to balance the charge of the iridium center.This complex is known for its luminescent properties and finds applications in fields such as organic light-emitting diodes (OLEDs), where the unique photophysical characteristics of the iridium center play a crucial role in light emission processes. The presence of the difluorophenyl groups in the ligands can influence the complex emission wavelengths and efficiency, contributing to its potential in optoelectronic devices.The combination of the bipyridine and difluorophenylpyridine ligands around the iridium ion results in a specific coordination environment that influences the complex stability, reactivity, and optical properties. | price> |