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Branaplam CAS No.1562338-42-4
Branaplam CAS No.1562338-42-4
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-4583 | 10mg | 310.00 | + Add to cart |
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| R-R-4583 | 25mg | 620.00 | + Add to cart |
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Product description
Branaplam (LMI070; NVS-SM1)/CAS No.1562338-42-4 is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model.
| Appearance | N/A |
|---|---|
| Molecular Weight | 393.48 |
| Purity | >90% |
| CAS | 1562338-42-4 |
| Formula | C22H27N5O2 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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