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Catalog	name	Description	price
R-C-2906	PLGA-b-PPG	Block copolymer micelles are polymer micelles with core-shell structure spontaneously formed by amphiphilic block copolymers dissolved in water to complete the solubilization and encapsulation of drugs. Most of their carriers are synthetic, biodegradable and thermodynamically stable in aqueous media.	price>
R-C-3036	SF1126 CAS:936487-67-1	SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibitor LY294002/SF1101 conjugated to the RGD-containing tetra-peptide SF1174 with potential antineoplastic and antiangiogenic activities.Only for scientific research, not for human body.	price>
R-R-4576	Streptozotocin CAS No.18883-66-4	Streptozotocin (Streptozocin)/CAS No.18883-66-4 is an antibiotic widely used in experimental animal models of induced diabetes. Streptozotocin enters B cells via the glucose transporter (GLUT2) and causes the alkylation of DNA ( DNA-methylating ). Streptozotocin can induce the apoptosis of β cells.	price>
R-R-4577	ART558 CAS No.2603528-97-6	ART558/CAS No.2603528-97-6 is a nanomolar potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM). ART558 can be used for the research of cancer.	price>
R-C-2908	PPO-PEO-PPO	poly(propylene oxide)-poly(ethylene oxide)-poly(propylene oxide) block copolymer is a series of water-soluble non-ionic surfactants composed of different PPO / PEO block ratio and molecular weight. Due to its good temperature response and biocompatibility, PEO-PPO-PEO block copolymers have important applications in the fields of hydrophobic drug solubilization and controlled release, gene therapy and so on.	price>
R-R-4578	Propidium Iodide CAS No.25535-16-4	Propidium Iodide (PI)/CAS No.25535-16-4 is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.	price>
R-C-2909	PEO-PPG-PEO	Block copolymer micelles are polymer micelles with core-shell structure spontaneously formed by amphiphilic block copolymers dissolved in water to complete the solubilization and encapsulation of drugs. Most of their carriers are synthetic, biodegradable and thermodynamically stable in aqueous media.	price>
R-R-4579	Gemcitabine hydrochloride CAS No.122111-03-9	Gemcitabine Hydrochloride (LY 188011 Hydrochloride)/CAS No.122111-03-9 is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis.	price>
R-C-2910	PEO-PBO	Block copolymer micelles are polymer micelles with core-shell structure spontaneously formed by amphiphilic block copolymers dissolved in water to complete the solubilization and encapsulation of drugs.Most of their carriers are synthetic,biodegradable and thermodynamically stable in aqueous media.	price>
R-R-4580	Remdesivir CAS No.1809249-37-3	Remdesivir (GS-5734)/CAS No.1809249-37-3, a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells and 30 nM for murine hepatitis virus in brain tumor cells delayed. Remdesivir is highly effective in controlling SARS-CoV-2 (COVID-19) infection in vitro.	price>
R-C-2911	P3-4HB-PEG	Through the selective coupling reaction between hydroxyl terminated P3-4HB segment and isocyanate end group, an alternating block polyurethane ppg-peg-ppg segment based on poly 3-hydroxybutyrate-co-4-hydroxybutyrate (P3-4HB glycol) and poly propylene glycol polyethylene glycol poly propylene glycol (ppg-peg-ppg) was synthesized, using 1,6-hexamethylene diisocyanate (HDI) as capping agent.	price>
R-R-4581	Brequinar CAS No.96187-53-0	Brequinar (DUP785)/CAS No.96187-53-0 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 5.2 nM for human DHODH. Brequinar has potent activities against a broad spectrum of viruses. Brequinar also has an anti-SARS2 activity.	price>
R-C-2912	PHBHHx-PEG	Hydroxybutyric acid and hydroxyhexanoic acid copolymer (PHBHHx),When the ratio of PHBHHx to peg is 3:1and 2 :1,they are completely physically compatible.The increase of the proportion of PEG in the blend leads to phase separation and becomes a partially compatible system.PEG incorporation significantly improved the hydrophilicity and surface free energy of the materials,and significantly improved the cell adhesion and proliferation of vascular smooth muscle cells(RASMCs)and vascular endothelial cells(HUVECs),both of which were dependent on PEG content.	price>
R-R-4582	a-Amanitin CAS No.23109-05-9	α-Amanitin/CAS No.23109-05-9 is the principal toxin of several deadly poisonous mushrooms, exerting its toxic function by inhibiting RNA-polymerase II.	price>
R-C-2913	PSO-PEO-PSO	RuixiBiotechCo.Ltd sells drug delivery and nano targetrelated R&D reagents, our products are phospholipid, polyethylene glycolderivatives, block copolymers, gold nanoparticles, magnetic nanoparticles,fluorescent dyes, microsphere.	price>
R-R-4583	Branaplam CAS No.1562338-42-4	Branaplam (LMI070; NVS-SM1)/CAS No.1562338-42-4 is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model.	price>
R-R-4584	Plicamycin CAS No.18378-89-7	Plicamycin (Mithramycin A)/CAS No.18378-89-7 is a selective specificity protein 1 (Sp1) inhibitor. Plicamycin inhibits the growth of various cancers by decreasing Sp1 protein. Plicamycin inhibits GSTM2 promoter activity and protein expression.	price>
R-C-2915	PAMAM-PEG-Active esters	Polyamide amine dendrimer (PAMAM) is one of the earliest synthesized dendrimers. It is monodisperse, with a cavity inside and a high-density amine group on the surface. As an excellent nano single molecule surfactant, it has good solubilization, demulsification and stability. It has very good practical value in emulsion explosive, oil exploitation, sewage treatment and drug solubilization.	price>
R-R-4585	GS-441524 CAS No.1191237-69-0	GS-441524/CAS No.1191237-69-0, predominant metabolite of Remdesivir and superior to Remdesivir against Covid-19 , shows comparable efficacy in cell-based models of primary human lung and cat cells infected with coronavirus. GS-441524 could strongly inhibits feline infectious peritonitis virus (FIPV), with an EC50 of 0.78 μM.	price>
R-R-4586	Novobiocin sodium CAS No.1476-53-5	Novobiocin (Albamycin) sodium/CAS No.1476-53-5 is a potent and orally active antibiotic. Novobiocin sodium also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin sodium has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin sodium shows anti-orthopoxvirus activity.	price>

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