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Catalog	name	Description	price
R-R-4132	CB1/2 agonist 1	CB1/2 agonist 1 is a potent and cross the blood-brain barrier CB1/2 agonist with EC50s of 56.15, 11.63 nM for CB1R and CB2R, respectively. CB1/2 agonist 1 reduces glutamate release and LPS-induced activation of microglial cells. CB1/2 agonist 1 shows anti-inflammatory and antinociceptive effects. CB1/2 agonist 1 has the potential for the research of multiple sclerosis.	price>
R-C-2433	Donepezil CAS:120014-06-4	Donepezil is a noncompetitive acetylcholineesterase inhibitor,which can readily cross the blood brain barrier and increase the concentration of cortical acetylcholine.It is known that Donepezil is a useful tool in the study of Alzheimer is disease.	price>
R-R-4133	2-Linoleoyl glycerol CAS No.3443-82-1	3-Linoleoyl glycerol (2-Monolinolein; 2-Monolinoleoylglycerol)/CAS No.3443-82-1 is a monoacylglycerol that is an antagonist and partial agonist at the type 1 cannabinoid CB1 receptor. The potency of 2-Linoleoyl glycerol can be enhanced by JZL195 (HY-15250), an inhibitor of FAAH and MAGL, and inhibited by the CB1 antagonist AM251 (HY-15443) and Cannabidiol. As a CB1 antagonist, 2-Linoleoyl glycerol does not enhance, but only attenuates, the activity of the CB1/CB2 receptor ligands cannabinoids (AEA) and 2-arachidonoylglycerol (2-AG).	price>
R-C-2434	Nodakenetin CAS:495-32-9	Nodakenetin(NANI),a plant-derived coumarin isolated from Angelica decursiva, inhibits α-glucosidase,PTP1B,rat lens aldose reductase(RLAR),AChE,BChE,and β-site amyloid precursor protein cleaving enzyme 1(BACE1).Nodakenetin alters the protein expression of Bax and Bcl-2,and prompts mitochondrial apoptosis.Nodakenetin exhibits anti-tumor activity.	price>
R-R-4134	PSNCBAM-1 CAS No.877202-74-9	PSNCBAM-1/CAS No.877202-74-9 is a selective CB1 receptor allosteric antagonist with an EC50 of 0.1 μM. PSNCBAM-1 can be used in the researches of obesity.	price>
R-C-2435	Hyoscyamine CAS:101-31-5	Hyoscyamine is a tropane alkaloid.It is a secondary metabolite found in certain plants of the Solanaceae family.It is the levorotary isomer of atropine and thus sometimes known as levo-atropine.Hyoscyamine is used to provide symptomatic relief to various gastrointestinal disorders including spasms,peptic ulcers, irritable bowel syndrome,pancreatitis,colic and cystitis.	price>
R-R-4135	RTICBM-189 CAS No.551909-15-0	RTICBM-189/CAS No.551909-15-0 is a potent, brain-penetrant allosteric modulator of the cannabinoid type-1 (CB1) receptor with a pIC50 of 7.54 in Ca2+ mobilization assay. RTICBM-189 has pIC50s of 5.29 and 6.25 for hCB1 and mCB1, respectively. RTICBM-189 significantly and selectively attenuates the reinstatement of the addictive agent-seeking behavior in rats.	price>
R-C-2436	Huperzine B CAS:103548-82-9	Huperzine B is a efficient inhibitor of human brain AChE,it can enhance ognitive and protect neuro.	price>
R-R-4136	ZCZ011 CAS No.1998197-39-9	ZCZ011/CAS No.1998197-39-9 is a potent and brain penetrant cannabinoid 1 (CB1) receptor positive allosteric modulator. ZCZ011 potentiates binding of CP55,940 to the CB1 receptor, enhances anandamide (AEA)-stimulated GTPγS binding in mouse brain membranes. ZCZ011 increases β-arrestin recruitment and ERK phosphorylation in hCB1 cells. ZCZ011 can be used for researching neuropathic and inflammatory pain.	price>
R-C-2437	Picfeltarraenin IB CAS:97230-46-1	Picfeltarraenin IB,a cucurbitacin glycoside isolated from Picriafel-terrae,is an inhibitor of acetylcholinesterase(AChE).Picfeltarraenin IB can be used for the treatment of herpes infections,cancer and inflammation.	price>
R-R-4137	AEF0117 CAS No.1610878-71-1	AEF0117/CAS No.1610878-71-1 is a signaling-specific inhibitor of the cannabinoid receptor 1 (CB1-SSi). AEF0117 plays an important role in Cannabis use disorder (CUD).	price>
R-C-2438	Imidafenacin CAS:170105-16-5	Imidafenacin(KRP-197,ONO-8025)is a urinary antispasmodic of the anticholinergic class.Imidafenacin(KRP-197;ONO-8025)is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM;less potent for M2 receptors(IC50=4.13nM).IC50 value:0.3nM(M3).	price>
R-R-4138	CB2 receptor agonist 2 CAS No.1314230-75-5	CB2 receptor agonist 2/CAS No.1314230-75-5 is a potent and selective agonist for the CB2 (cannabinoid type 2) receptor with a Ki of 8.5 nM. CB2 receptor agonist 2 has high affinity and selectivity for CB2.	price>
R-C-2439	Edrophonium chloride CAS:116-38-1	Edrophonium Chloride,also known as Tensilon,is an acetylcholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. Edrophonium Chloride has also been used as an antidote to curare principles.	price>
R-R-4139	PSB-SB-487 CAS No.1399049-81-0	PSB-SB-487/CAS No.1399049-81-0 is a potent GPR55 antagonist and CB2 agonist with an IC50 value of 0.113 µM for GPR55, and a Ki value of 0.292 µM for human CB2. PSB-SB-487 can be used for researching diabetes, Parkinson’s disease, neuropathic pain, and cancer.	price>
R-C-2440	Corydaline CAS:518-69-4	Corydaline is a bioactive alkaloid with various anti-acetylcholinesterase,anti-allergic,and anti-nociceptive activities found in the medicinal herb Corydalis Tubers.	price>
R-R-4140	CB2 receptor agonist 3 CAS No.919077-81-9	CB2 receptor agonist 3/CAS No.919077-81-9 is a robust and selective CB2 cannabinoid agonist with Kis of 7.6 and 900 nM for CB2 and CB1, respectively. CB2 receptor agonist 3 significantly increases P-ERK 1/2 expression in HL-60 cells.	price>
R-C-2441	Atracurium Besylate CAS:64228-81-5	Atracurium Besilate is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs,used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.	price>
R-R-4141	(Rac)-Zevaquenabant CAS No.1610420-28-4	(Rac)-Zevaquenabant ((Rac)-MRI-1867/CAS No.1610420-28-4, compound 6b) is a cannabinoid receptor type 1 (CB1R)/iNOS antagonist, with a Ki of 5.7 nM for CB1R. (Rac)-Zevaquenabant is potential for the research of liver fibrosis.	price>
R-C-2442	Nodakenin CAS:495-31-8	Nodakenin acts as an AChE inhibitor that inhibits AChE activity in a dosedependent manner with an IC50 value of 84.7uM.Nodakenin possesses neuroprotective,anti-allergic,antiaggregatory,antibacterial,and memory -enhancing effects.Nodakenin down-regulates the expression of the proinflammatory iNOS,COX-2,TNF-α,IL-6,and IL-1β genes in macrophages by interfering with the activation of TRAF6,thus preventing NF-κB activation.	price>

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