Hispidulin CAS:1447-88-7

Hispidulin(Dinatin),an active natrual ingredient in a number of traditional Chinese medicinal herbs,exhibits inhibitory activity against the oncogenic protein kinase Pim-1 with IC50 of 2.71μM.Hispidulin induces apoptosis through mitochondrial dysfunction and inhibition of P13k/Akt signalling pathway in HepG2 cancer cells.Hispidulin exerts anti-osteoporotic and bone resorption attenuating effects via activating the AMPK signaling pathway.

msds---Hispidulin