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| Catalog | name | Description | price |
|---|---|---|---|
| R-R-2522 | MT1 CAS No.2060573-82-0 | MT1/CAS No.2060573-82-0 is a bivalent chemical probe of BET bromodomains, with an IC50 of 0.789 nM for BRD4. | price> |
| R-C-823 | Cis-aconitic anhydride-d-tyrosine(CA-DTyr) | The surface of polyethersulfone(PES)membrane was modified with D-Tyrosine to improve the hydrophilicity and antibacterial properties of the membrane surface, thus alleviating the membrane biofouling.The surface hydrophilicity of the membrane was increased,the roughness was reduced,and the permeability of the membrane was not affected. | price> |
| R-R-2523 | GNE-375 CAS No.1926989-06-1 | GNE-375/CAS No.1926989-06-1 is a potent and highly selective BRD9 inhibitor with an IC50 of 5 nM. GNE-375 shows >100-fold selective for BRD9 over BRD4, TAF1, and CECR2. GNE-375 decreases BRD9 binding to chromatin. | price> |
| R-C-824 | Bleomycin hydrochloride(cas:67763-87-5) | Bleomycin hydrochloride is a member of bleomycin putrefycin antibiotic family.It is a water-soluble,copper ion chelating glycoprotein antibiotic isolated from Streptomyces verticillius.The presence of copper ions makes the solution blue. The chelating form of copper ion is inactive.When antibiotics enter the cell, cu2+is reduced to cu+,and is removed by the mercaptol compounds in the cell.At this time,bleomycin hydrochloride is activated and combined with DNA,and DNA is cut,which causes cell death.The protein encoded by the bleomycin tolerance gene (SH ble)can bind with bleomycin hydrochloride and inhibit the DNA cutting by bleomycin hydrochloride.Bleomycin hydrochloride has a wide spectrum of action, which has strong antibacterial activity to bacteria,fungi(including yeast), plants and mammalian cells.Therefore,bleomycin hydrochloride is often used as a very effective tool antibiotic to screen a cell line with SH ble resistance gene and stably express 13.665 kDa. | price> |
| R-R-2524 | I-BET282 CAS No.1422554-34-4 | I-BET282/CAS No.1422554-34-4 is a pan-inhibitor of all eight BET bromodomains, and selectivity over other representative bromodomain-containing proteins. I-BET282 shows pIC50s ranging 6.4-7.7 for BRD2 (BD1/BD2), BRD2 (BD1/BD), BRD3 (BD1/BD), and BRD4 (BD1/BD). | price> |
| R-C-825 | Ce6-SH | CE6 is usually synthesized from pheophorbidic acid A.It is a good photosensitizer with similar biological activity to pheophorbidic acid a.CE6 is highly efficient in producing singlet oxygen because it is suitable for developing photodynamic therapy for tumors. | price> |
| R-R-2525 | MI-3 CAS No.1271738-59-0 | MI-3 (Menin-MLL inhibitor 3)/CAS No.1271738-59-0 is a potent and high affinity menin-MLL inhibitor with an IC50 of 648 nM and a Kd of 201 nM. | price> |
| R-C-826 | PS6500-graft-PEG4600-COOH | Polystyrene(PS)is a kind of polymer synthesized by free radical addition reaction of styrene monomer,and polyethylene glycol(PEG)is an oligomer or polymer of ethylene oxide.The product is non-toxic,non irritant,slightly bitter in taste,good in water solubility and good in compatibility with many organic components. | price> |
| R-R-2526 | ZL0590 CAS No.2230496-99-6 | ZL0590/CAS No.2230496-99-6 is a potent, orally active BRD4 BD1-selective inhibitor with an IC50 of 90 nM for human BRD4 BD1. ZL0590 exhibits significant anti-inflammatory activities. | price> |
| R-C-827 | NBD-DMPE | Ruixibio can provide NBD-1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine as well as various products with other labels.For example,1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine(DMPE)and NBD regulated polyethylene glycol,DMPE peg NBD is a fluorescent phospholipid peg converge that can be used as fluorescent lipid membrane probe. | price> |
| R-R-2527 | Menin-MLL inhibitor 20 CAS No.2448173-47-3 | Menin-MLL inhibitor 20/CAS No.2448173-47-3 is an irreversible menin-MLL interaction inhibitor with antitumor activities (WO2020142557A1, Intermediate 6). | price> |
| R-C-828 | Rho-DMPE | When NBD-DMPE is excited at 460 nm,the resulting solution emits fluorescence at 530 and 588 nm,reflecting the emission of nbd-dmpe and Rho DMPE,respectively. After one or more cycles of freeze-thawing,the fluorescence intensity at 530 nm increased with the increase of cycle times,and the fluorescence intensity decreased at 588 nm. | price> |
| R-R-2528 | GS-626510 CAS No.1637770-13-8 | GS-626510/CAS No.1637770-13-8 is a potent, and orally active BET family bromodomains inhibitor, with Kd values of 0.59-3.2 nM for BRD2/3/4, with IC50 values of 83 nM and 78 nM foe BD1 and BD2, respectively. | price> |
| R-C-829 | NHS-PEG2000-RGD | Polyethylene glycol(PEG)is a kind of high molecular polymer,which has no irritation,slightly bitter taste,good water solubility and good compatibility with many organic components.RGD sequence is composed of arginine,glycine and aspartic acid,and exists in a variety of extracellular matrix.It can specifically bind with 11 integrins,which can effectively promote cell adhesion to biomaterials. | price> |
| R-R-2529 | CBP/p300-IN-8 CAS No.2304416-91-7 | CBP/p300-IN-8/CAS No.2304416-91-7 is a potent inhibitor of the CBP/P300 family of bromodomains. CBP/p300-IN-8 inhibits CBP (IC50=0.01-0.1 µΜ) and BRD4 (IC50=1-1000 µΜ) activity. | price> |
| R-C-830 | PLGA5K-hyd-PEG5K | Poly(lactic co glycolic acid)-Hyde poly(ethylene glycol)is a kind of amphiphilic block copolymer,which is linked by the acid sensitive chemical bond of hydrazone bond.The micelle products made by this product can break and release drugs in the fixed pH environment. | price> |
| R-R-2530 | NI-42 CAS No.1884640-99-6 | NI-42 (compound 13-d)/CAS No.1884640-99-6, a structurally orthogonal chemical probe for the BRPFs, is a biased, potent inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM) with excellent selectivity over nonclass IV BRD proteins. | price> |
| R-C-831 | Encapsulation of Fe3O4 by Cy5 labeled peg cationic liposomes | Cy5 labeled PEGylated cationic liposomes containing Fe3O4 are provided by Ruixi biological Co.,Ltd.we can also provide CY labeled peptide antibody protein and polysaccharide products. | price> |
| R-R-2531 | M-1211 CAS No.2377337-93-2 | M‑1121/CAS No.2377337-93-2 is a covalent and orally active inhibitor of the menin-MLL interaction capable of achieving complete and persistent tumor regression. | price> |
| R-C-832 | PLGA5K-PEG2K-TAT(YGRKKRRQRRRC) | PLGA-PEG-TAT,PLGA-PEG-YGRKKRRQRRRC,Targeted transmembrane peptide(TAT)(ygrkrrqrrr-nh2)is a classic cell transmembrane peptide,which has strong cell penetrating power and can directly act on the nucleus.Poly (lactic co glycolic acid)is a kind of degradable functional polymer,which is randomly polymerized by two monomers lactic acid and glycolic acid.It has good biocompatibility,non-toxic,good properties of encapsulation and film formation.It is widely used in pharmaceutical,medical engineering materials and modern industrial fields. | price> |

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