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Catalog	name	Description	price
R-R-2479	dBET57 CAS No.1883863-52-2	dBET57/CAS No.1883863-52-2 is a potent and selective degrader of BRD4BD1 based on the PROTAC technology. dBET57 mediates recruitment to the CRL4Cereblon E3 ubiquitin ligase, with a DC50/5h of 500 nM for BRD4BD1, and is inactive on BRD4BD2.	price>
R-R-2480	ZL0580 CAS No.2377151-10-3	ZL0580/CAS No.2377151-10-3, a structurally close analog of ZL0590, induces epigenetic suppression of HIV via selectively binding to BD1 domain of BRD4. ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter.	price>
R-R-2481	PROTAC BRD4 ligand-1 CAS No.2313230-51-0	PROTAC BRD4 ligand-1/CAS No.2313230-51-0 is a potent BET inhibitor and a ligand for target BRD4 protein for PROTACT GNE-987 (HY-129937A).	price>
R-C-782	MAL-PEG113-PLys	Maleimide is an organic compound,chemical formula is c4h3no2,flake crystal,easy to sublimate,soluble in water,ether and ethanol.Polyethylene glycol(PEG)is a kind of high molecular polymer,which has no irritation,slightly bitter taste,good water solubility and good compatibility with many organic components.The two ends of PEG are linked with mal and polylysine.	price>
R-R-2482	CBP/p300-IN-12 CAS No.2738688-57-6	CBP/p300-IN-12/CAS No.2738688-57-6 is a potent and selective covalent histone acetyltransferases p300 (IC50 of 166 nM) and CBP inhibitor. CBP/p300-IN-12 decreases the levels of H3K27Ac of PC-3 cells (EC50 of 37 nM). CBP/p300-IN-12 forms a covalent adduct with C1450.	price>
R-C-783	TCO-PEG5000-Maleimide	As a kind of amphiphenyl,trans cyclooctene(TCO)has the advantages of no catalyst and fast reaction rate in physiological conditions.It has been widely used in the research of biology and materials science.Peg can enhance solubility and stability,reduce the surface non-specific binding of charged molecules,and reduce the immunogenicity of polypeptide.	price>
R-R-2483	PF-CBP1 hydrochloride CAS No.2070014-93-4	PF-CBP1 hydrochloride/CAS No.2070014-93-4 is a highly selective inhibitor of the CREB binding protein bromodomain (CBP BRD). PF-CBP1 inhibits CREBBP and EP300 bromodomains with IC50 of 125 nM and 363 nM respectively. PF-CBP1 hydrochloride reduces LPS-induced inflammatory cytokines expression (IL-1β, IL-6 and IFN-β) in primary macrophages. PF-CBP1 hydrochloride also downregulates RGS4 expression cortical neurons and can be used for the research of neurological disorders.	price>
R-R-2484	BAY1238097 CAS No.1564268-08-1	BAY1238097/CAS No.1564268-08-1 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple myeloma) models through down-regulation of c-Myc levels and its downstream transcriptome (IC50 <100 nM).	price>
R-C-785	PBA-PEG1000-cRGD	1-Pyrenebutyric acid(PBA)is a conjugated polymer that has a large π system and a carboxylic group.It is majorly used in surface functionalization.It has a high fluorescence efficiency and stability that make it useful in optoelectronic applications.	price>
R-R-2485	(S)-JQ-35 CAS No.1349719-98-7	(S)-JQ-35 (TEN-010)/CAS No.1349719-98-7 is an inhibitor of the Bromodomain and Extra-Terminal (BET) family bromodomain-containing proteins with potential antineoplastic activity.	price>
R-C-786	Compound customization (Rhodamine fluorescence)	Rhodamine is a laser dye,which is used for biological dyeing.It is a fluorescent dye,catechol.Rhodamine B is mainly used for industrial dyeing,and it is fat soluble.Rhodamine B has strong fluorescence in solution,so it can be used as fluorescent staining agent in laboratory.	price>
R-R-2486	ACBI2 CAS No.2913161-19-8	ACBI2/CAS No.2913161-19-8 is a highly potent and orally active VHL PROTAC SMARCA2 degrader (EC50: 7 nM), which selectively degrades SMARCA2 with a DC50 value of 1 nM in RKO cells. ACBI2 can be used in the research of lung cancer.	price>
R-C-787	18：1DGS_NTA	1,2-dioleoyl-sn-glycero-3-[(n-(5-amino-1-carboxyphenyl)iminodiacetic acid) succenyl](nickel salt)is a customized product from Ruixi biotechCo.Ltd.	price>
R-R-2487	GSK620 CAS No.2088410-46-0	GSK620/CAS No.2088410-46-0 is a potent and orally active pan-BD2 inhibitor with excellent broad selectivity, developability and in vivo oral pharmacokinetics. GSK620 is highly selective for the BET-BD2 family of proteins, with >200-fold selectivity over all other bromodomains. GSK620 shows an anti-inflammatory phenotype in human whole blood.	price>
R-C-788	COOH-PEG1000-chitosan20000	Chitosan,also known as deacetylated chitin,is obtained by deacetylation of chitin, which widely exists in nature.Polyethylene glycol is an adduct of polyethylene oxide and water.	price>
R-R-2488	MI-538 CAS No.1857417-10-7	MI-538/CAS No.1857417-10-7 is an inhibitor of the interaction between menin and MLL fusion proteins with an IC50 of 21 nM.	price>
R-R-2489	CFT8634 CAS No.2704617-96-7	CFT8634/CAS No.2704617-96-7 is an oral activity degrader targeting BRD9 extracted from patent WO2021178920A1 compound 174. CFT8634 can be used for the research of synovial sarcoma and SMARCB1-deleted solid tumors.	price>
R-C-790	Inorganic composite nanomaterials（Ag Mn Au）	Nano materials refer to the macro materials formed by the accumulation of nanostructures in a certain way or dispersion in a certain matrix.Nano particles have special physical and chemical properties,which can be widely used in chemical industry,biology,medicine and other fields.	price>
R-R-2490	INCB-057643 CAS No.1820889-23-3	INCB-057643/CAS No.1820889-23-3 is a novel, orally bioavailable BET inhibitor.	price>
R-C-791	Oleic acid modified MnFe2O4 3NM	The MnFe2O4 nanocrystals modified by oleic acid are prepared by pyrolysis at high temperature.They can be stably dispersed in toluene or cyclohexane with a concentration of 5mg/ml,which is provided by Ruixi biological company.	price>

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