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Catalog	name	Description	price
R-mo-288	CCOF-6,Chiral covalent organic frameworks-6	CCOF-6, Chiral covalent organic frameworks-6 from ruixi.CCOF was synthesized from chiral taddol precursor with helical structure and diamine precursor with flexible structure. It is a covalent organic framework material with double interpenetrating network.CCOF-6 has separation performance,can be used as a chiral stationary phase for the separation of racemic alcohols.	price>
R-R-1422	PF-543 Citrate CAS No.1415562-83-2	PF-543 Citrate (Sphingosine Kinase 1 Inhibitor II Citrate)/CAS No.1415562-83-2 is a potent, selective, reversible and sphingosine-competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3.6 nM. PF-543 Citrate is >100-fold selectivity for SPHK1 over SPHK2. PF-543 Citrate is an effective potent inhibitor of sphingosine 1-phosphate (S1P) formation in whole blood with an IC50 of 26.7 nM. PF-543 Citrate induces apoptosis, necrosis, and autophagy.	price>
R-OR-322	Poly-DL-alanine ,CAS: 25281-63-4	Poly-DL-alanine ,CAS: 25281-63-4 Poly-DL-alanine ,CAS: 25281-63-4 from ruixi The Raman spectrum of poly‐DL‐alanine (PDLA) in the solid state is interpreted in terms of the disordered chain conformation, in analogy with the spectrum of mechanically deformed poly‐L‐alanine. The polymer is largely disordered with only a small α‐helical content in the solid state. When PDLA is dissolved in water, the spectra suggest that short α‐helical segments are formed upon dissolution. These helical regions might be stabilized by hydrophobic bonds between side‐chain methyl groups.	price>
R-mo-289	COF-BPDA,Chiral covalent organic framework-3,3,4,4-biphenyltetracarboxylic dianhydride	COF-BPDA,Chiral covalent organic framework-3,3,4,4-biphenyltetracarboxylic dianhydride from ruixi.CCOF was synthesized from chiral taddol precursor with helical structure and diamine precursor with flexible structure. It is a covalent organic framework material with double interpenetrating network.	price>
R-R-1423	12-HETE-d8 CAS No.2525175-25-9	12-HETE-d8/CAS No.2525175-25-9 is the deuterium labeled 12-HETE. 12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway.12-HETE has both anti-thrombotic and pro-thrombotic effects. 12-HETE is a neuromodulator.	price>
R-OR-323	Poly-L-threonine,CAS:82822-12-6	Poly-L-threonine,CAS:82822-12-6 Poly-L-threonine,CAS:82822-12-6 from ruixi Amino acids, as a kind of very important life substance, are widely used in medicine, biology, chemistry and other fields. Up to now, most of the researches on amino acids have focused on synthesis, characterization and the role in genetic function.	price>
R-mo-290	SIOC-COF-1,SIOC-covalent organic framework-1	SIOC-COF-1,SIOC-covalent organic framework-1 from ruixi.The advantages of COFS: low density, high specific surface area,easy modification and functionalization.COFS can be used in gas storage and separation,heterogeneous catalysis,energy storage materials,optoelectronics,sensing and drug delivery.	price>
R-R-1424	SKI-178 CAS No.1259484-97-3	SKI-178/CAS No.1259484-97-3 is a potent sphingosine kinase-1 (SphK1) and SphK2 inhibitor. SKI-178 is cytotoxic at IC50 concentrations ranging from 1.8 to 0.1 μM in both agent sensitive and multi-agent resistant cancer cell lines (i.e., MTR3, NCI-ADR and HL60/VCR cells). SKI-178 induces apoptosis in a CDK1-dependent manner in human acute myeloid leukemia cell lines.	price>
R-OR-324	Poly-L-histidine ,CAS:26062-48-6	Poly-L-histidine ,CAS:26062-48-6 Poly-L-histidine ,CAS:26062-48-6 from ruixi Poly-L-histidine is an amphoteric compound. The imidazole ring in its structure enables protonation−deprotonation. Application Poly-L-histidine has been used: • as a polycation for the dispersion of multi-wall carbon nanotubes (MWCNTs) • as a polyionic compound to investigate its ability to rupture extracellular enveloped virus membrane.	price>
R-mo-291	SIOC-COF-2,SIOC-covalent organic framework-2	SIOC-COF-2,SIOC-covalent organic framework-2 from ruixi.The advantages of COFS: low density, high specific surface area,easy modification and functionalization.COFS can be used in gas storage and separation,heterogeneous catalysis,energy storage materials,optoelectronics,sensing and drug delivery.	price>
R-R-1425	Z-FA-FMK CAS No.197855-65-5	Z-FA-FMK ((1S)-Z-FA-FMK)/CAS No.197855-65-5 is a potent Cathepsin B and L inhibitor. Z-FA-FMK blocks the induction of DEVDase activity, DNA fragmentation, and externalization of phosphatidylserine by selective synthetic retinoid-related molecules (RRMs). Z-FA-FMK inhibits apoptosis. Z-FA-FMK inhibits caspase activity and selectively inhibits recombinant effector caspases 2, -3, -6, and -7. Z-FA-FMK is a viral inhibitor. Z-FA-FMK inhibits reovirus replication in a susceptible host.	price>
R-OR-325	Poly-L-tyrosine ,CAS:25619-78-7	Poly-L-tyrosine ,CAS:25619-78-7 Poly-L-tyrosine ,CAS:25619-78-7 from ruixi Poly-l-tyrosine has the properties of peptide which are required by biocompatibility, biodegradability, non toxicity and non immunogenicity. It has good processability, including solubility, thermal stability and formability, which are produced by alternating non amide bonds along the main chain of polymer.	price>
R-OOR-325	Poly-L-aspartic acid ,CAS：25608-40-6	Poly-L-aspartic acid ,CAS：25608-40-6 Poly-L-aspartic acid ,CAS：25608-40-6 from ruixi Poly-L-aspartic acid sodium salt is a negatively charged synthetic polyamino acid having one Na per aspartic acid unit. It is a crystalline solid soluble in water. Applications for poly-L-aspartic acid sodium salt include the conjugation to active molecules for improved activities, the layer-by-layer deposition techniques for surface coating, the mineralization of bone, and the water treatment.	price>
R-mo-292	TPA-COF,1,3,5-trihydroxy pyromellitic aldehyde-covalent organic framework	TPA-COF,1,3,5-trihydroxy pyromellitic aldehyde-covalent organic framework from ruixi.Tp-cof is a kind of COF material with fluorescence properties.The advantages of COFS: low density, high specific surface area, easy modification and functionalization.COFS can be used in gas storage and separation, heterogeneous catalysis, energy storage materials, optoelectronics, sensing and drug delivery.	price>
R-R-1426	Fasentin CAS No.392721-37-8	Fasentin/CAS No.392721-37-8, a potent glucose uptake inhibitor, inhibits GLUT-1/GLUT-4 transporters. Fasentin preferentially inhibits GLUT4 (IC50=68 μM) over GLUT1. Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death. Fasentin is also a tumor necrosis factor (TNF) apoptosis-inducing ligand sensitizer. Fasentin blocks glucose uptake in cancer cell lines and has anti-angiogenic activity.	price>
R-OR-326	Poly-Glutamic Acid(sodium salt) cas:26247-79-0	Poly-L-Glutamic Acid(sodium salt) cas:26247-79-0 Poly-Glutamic Acid(sodium salt) cas:26247-79-0 from ruixi Polyglutamic acid (γ - PGA), also known as natto gum and polyglutamic acid, is a kind of water-soluble, biodegradable, non-toxic biopolymer produced by microbial fermentation. γ - PGA polyglutamic acid is a viscous substance.γ - PGA polyglutamic acid is a special anionic natural polymer.	price>
R-M-001	NT-COF,NT-covalent organic framework	NT-COF,NT-covalent organic framework from ruixi.NT-COF is a covalent organic framework material connected by naphthalene diimide (NDI)and triphenylamine(TPA) units. It is also a bifunctional material with light absorption and reversible electrochemical energy storage.Nt-cof was filled with two-dimensional porous nanosheets with a high specific surface area of 1276 m2/ g.	price>
R-R-1427	JGB1741 CAS No.1256375-38-8	JGB1741 (ILS-JGB-1741)/CAS No.1256375-38-8 is a potent and specific SIRT1 activity inhibitor with an IC50 of ∼15 μM. JGB1741 is a weak SIRT2 and SIRT3 inhibitor with an all IC50>100 μM. JGB1741 increases the acetylated p53 levels leading to p53-mediated apoptosis with modulation of Bax/Bcl2 ratio, cytochrome c release and PARP cleavage. JGB1741 has the potential for breast cancer research.	price>
R-OR-327	FITC-poly(L-alanine)	FITC-poly(L-alanine) FITC-poly(L-alanine) from ruixi FITC labeled polylysine.Poly-L-lysine, which is a natural product of biological metabolism. It has good bactericidal ability and thermal stability, and is a biological preservative with excellent antiseptic performance and great commercial potential. At the same time, it was found that ε - polylysine and other natural antimicrobial agents had obvious synergistic effect, which could improve its antibacterial ability.	price>
R-M-002	PI-COF-1,polyimide-covalent organic framework-1	PI-COF-1,polyimide-covalent organic framework-1 from ruixi.Covalent organic frameworks (COFS) are a new kind of porous crystalline polymers.PI-COF has high specific surface area, high temperature resistance and thermal stability up to 530 °C.PI-COF-1,polyimide-covalent organic framework-1 is a 2D crystal COF material with 33 hexagonal holes.	price>