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Cl-amidine hydrochloride CAS No.1373232-26-8
Cl-amidine hydrochloride CAS No.1373232-26-8
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-1414 | 10mg | 200.00 | + Add to cart |
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| R-R-1414 | 25mg | 410.00 | + Add to cart |
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Product description
Cl-amidine hydrochloride/CAS No.1373232-26-8 is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine hydrochloride induces apoptosis in cancer cells. Cl-amidine hydrochloride induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model.
| Appearance | N/A |
|---|---|
| Molecular Weight | 347.24 |
| Purity | >90% |
| CAS | 1373232-26-8 |
| Formula | C14H20Cl2N4O2 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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