Gedatolisib(PKI587) CAS:1197160-78-3
Gedatolisib(PKI587)
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-C-457 | 50mg | 582.00 | + Add to cart |
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R-C-457 | 100mg | 990.00 | + Add to cart |
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R-C-457 | 200mg | 1650.00 | + Add to cart |
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Product description
Gedatolisib (pf-05212384,pki-587) is a highly effective dual inhibitor of PI3K α,PI3K γ and mTOR.The IC50 of gedatolisib (pf-05212384,pki-587) is 0.4nm,5.4nm and 1.6nm in cell-free experiment,respectively.Pki-587 also showed potency against the most common PI3K mutation, especially h1047r and e545k,with IC50 of 0.6Nm and 0.6Nm,respectively.The inhibitory effect of pf-05212384 on PI3Ks and mtors inhibited the growth of mda-361 and pc3-mm2 cell lines with IC50 of 4 nm and 13.1 nm,respectively.
Appearance | N/A |
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Molecular Weight | N/A |
Purity | >95% |
PDI by GPC | <1.5 |
Solubility | Gedatolisib (pf-05212384,pki-587) is a highly effective dual inhibitor of PI3K α,PI3K γ and mTOR.The IC50 of gedatolisib (pf-05212384,pki-587) is 0.4nm,5.4nm and 1.6nm in cell-free experiment,respectively.Pki-587 also showed potency against the most commo |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
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