deguelin CAS:522-17-8

Deguelin,a naturally occurring rotenoid,acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt,IKK-NF-κB,and MAPK-mTOR-survivin-mediated apoptosis.Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins,including MEK1/2,Akt,HIF1α,COX-2,and NF-κB.

msds---deguelin