Bortezomib CAS:179324-69-7

Bortezomib(PS-341,Velcade,LDP-341,MLM341,NSC 681239)is a potent 20S proteasome inhibitor with Ki of 0.6 nM.It exhibits favorable selectivity towards tumor cells over normal cells.Bortezomib(PS-341)inhibits NF-κB and induces ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors.

msds---Bortezomib