Chicoric acid,cas:6537-80-0

Chicoric acid(C22H18O12,474.37) is a dicaffeoyl ester that has been found in C. intybus with diverse biological activities.Chicoric acid (50-200 μg/ml) dose-dependently reduces the viability of Caco-2 and HCT116 human colorectal cancer cells.It inhibits HIV integrase activities, including 3-processing of a DNA oligonucleotide and integration with template DNA (IC50s = 1.1 and 0.8 μM, respectively).Chicoric acid (0.5-10 μM) noncompetitively inhibits integration of HIV DNA by HIV integrase and, at concentrations greater than or equal to 5 μM, inhibits HIV entry into H9 cells.

msds of 2,3-Dicaffeoyl-L-tartaric acid