CMS121,cas:1353224-53-9
4-[4-(cyclopentyloxy)-2-quinolinyl]-1,2-benzenediol
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-XASYS-00045 | 10mg | 223.00 | + Add to cart |
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R-XASYS-00045 | 25mg | 498.00 | + Add to cart |
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Product description
CMS121(C20H19NO3,321.4) is a substituted quinoline that has neuroprotective, anti-inflammatory, antioxidative, and renoprotective activities.It maintains glutathione (GSH) levels in HT22 mouse hippocampal cells in vitro in the presence of glutamate, induces differentiation of PC12 cells, prevents LPS-induced N9 microglial activation by 82% in N9 microglia, and scavenges free radicals in a Trolox equivalent activity concentration (TEAC) assay.CMS121 protects against ischemia and oxytosis in phenotypic screens in HT22 cells in vitro with EC50 values of 7 and 200 nM for preventing iodoacetic acid- or glutamate-induced cell death, respectively.
Appearance | N/A |
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Molecular Weight | N/A |
Purity | >90% |
Solubility | N/A |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 3 weeks |
Stability | 1 year |
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