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Brevilin A,cas:16503-32-5

(2Z)-2-methyl-2-butenoic acid, 2,3S,3aR,4S,4aR,5,7aR,8R,9,9aR-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-yl ester

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-XASYS-00387 10mg 624.00
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R-XASYS-00387 25mg 1417.00
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Product description

Brevilin A(C20H26O5,346.4) is a sesquiterpene lactone that has been found in C. minima and has anticancer activity.It is an inhibitor of STAT3 signaling (IC50 = 10.6 µM in A549R cells) that inhibits the tyrosine kinase activity of the JAK1, JAK2, JAK3, and JAK4 JH1 subunit (IC50s = 11.2, 8.4, 10.2, and 11.9 µM, respectively).It inhibits proliferation of a variety of cancer cells, including A549 lung, HepG2 liver, HeLa cervical, A875 melanoma, and CT26 mouse colon carcinoma cells in a concentration-dependent manner.

Brevilin A,cas:16503-32-5

Appearance N/A
Molecular Weight N/A
Purity >90%
Solubility N/A
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 3 weeks
Stability 1 year
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