Product peptide-synthetic-peptide

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Catalog	name	Description	price
R-M-1466	A-779 Peptide,CAS :159432-28-7	A-779 Peptide is a selective angiotensin-(1-7) antagonist. This peptide is contained within Angiotensinogen which after processing regulates both the volume and the mineral balance in the body. A-779 peptide binds to Mas receptor with an IC50 of 0.3 nM.	price>
R-M-1468	Asp371 Tyrosinase [369-377] Peptide,Cas:168650-46-2	The peptide is a tumor antigenic peptide that activates antigen-presenting cells (APC) and is displayed on melanoma tumor cells. The sequence corresponds to the mutated N371D glycosylation site analog within residues 369-377 of human tyrosinase (TYR). The TYR enzyme is an oxidase that is involved in the formation of pigments such as melanins and other polyphenolic compounds by tyrosine conversion. TYR defects are the cause of oculocutaneous albinism, characterized by the absence of pigment in hair, skin and eyes.	price>
R-M-1470	[DES-ASP1]-ANGIOTENSIN I, HUMAN,Cas:100900-27-4	Angiotensin I (AT I) is a peptide cleavage product of angiotensin and serves no primary biological purpose other than to function as a precursor to angiotensin II.	price>
R-M-1472	ANGIOTENSIN I, HUMAN,Cas:484-42-4	Angiotensin I is a putative neurotransmitter. Angiotensin I is the precursor of angiotensin II and of angiotensin fragment 1-7, which are the hormones involved in regulation of fluid volume and the release of aldosterone.	price>
R-M-1474	ANGIOTENSIN II (1-4), HUMAN,Cas:52580-29-7	Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure. Angiotensin also potentiates the release of norepinephrine by a direct action on postganglionic sympathetic fibers.	price>
R-M-1486	RIGIN,Cas :77727-17-4	Rigin is a tuftsin-like tetrapeptide with the sequence G-Q-P-R that is derived from IgG. Rigin exhibits immunomodulatory activity, stimulating phagocytosis, activating polymorphonuclear lymphocytes and macrophages, and protecting against stress-induced damage.	price>
R-M-1498	EXENDIN-3,Cas :130357-25-4	Exendin-3 is an analog of glucagon-like peptide 1 (GLP-1); it acts as an agonist at GLP-1 receptors. Exendin-3 was originally found in Heloderma lizards. Like other GLP-1 agonists, this compound may exhibit anti-diabetic activity.	price>
R-M-1499	EXENDIN-4,Cas:141758-74-9	Exendin-4 is an analog of glucagon-like peptide 1 (GLP-1);it acts as an agonist at GLP-1 receptors. Exendin-4 exhibits cardioprotective, anti-inflammatory, and antioxidative activities. In mesangial cells, exendin-4 increases phosphorylation of AMPK and decreases phosphorylation of ERK, inhibiting fibronectin secretion and cell proliferation.	price>
R-M-1502	GLUCAGON-LIKE PEPTIDE I AMIDE (7-36), HUMAN,Cas : 107444-51-9	Glucagon-like peptide 1 (GLP-1) is an endogenous peptide hormone that binds GLP-1 receptors, increasing cAMP and insulin secretion. GLP-1 primarily exhibits anorexigenic, anti-diabetic, and gastrointestinal modulatory activities. GLP-1 decreases food intake and glucagon levels in animal models and also slows gastric emptying. In subjects with type 2 diabetes, the response of GLP-1 to glucose is impaired and subjects show abnormally low levels of GLPs.	price>
R-M-1509	PITUITARY ADENYLATE CYCLASE-ACTIVATING PEPTIDE (6-38), HUMAN/SHEEP/RAT	Pituitary adenylate cyclase-activating polypeptide (PACAP) is an endogenous peptide that stimulates cAMP production in the anterior pituitary. PACAP and PACAP-related peptide (PRP) regulate immune function and display increases in expression when hosts are challenged with bacterial pathogens. PACAP and PRP also control expression of reproductive hormones such as follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Additionally, PACAP and PRP bind the PAC1 receptor and VPAC1/2 receptors. PACAP itself inhibits K+ amplitude of delayed rectifier K+ channels, exhibiting anti-apoptotic activity in cerebellar granule cells.	price>

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