Product peptide-synthetic-peptide

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Catalog	name	Description	price
R-M-206	[tyr8] bk Peptide,Cas :32222-00-7	[Tyr8] Bradykinin Peptide, [tyr8] bk Peptide from ruixi.Bradykinin is a peptide that exhibits natriuretic, antioxidative, vasodilatory, and pro-angiogenic activities. Bradykinin stimulates bradykinin receptors and increases PLC activity, decreasing ENaC open probability, inhibiting distal nephron Na+ transport, and inducing natriuresis. In vitro, bradykinin decreases H2O2-induced senescence, increases activity of superoxide dismutase (SOD), and suppresses DNA damage, ROS production, and NADPH oxidase activity. Additionally, bradykinin increases expression of VEGF and promotes tube formation in prostate cancer cells.	price>
R-M-207	[Tyr4] Bombesin Peptide,CAS:67338-70-9	Bombesin, secreted by the toad skin glands, stimulates smooth muscle contraction.	price>
R-M-208	[Tyr1] Somatostatin Peptide	[Tyr1] Somatostatin Peptide is a 14-aa peptide that corresponds to aa 103-116 of somatostatin precursor before cleavage with a Tyr instead of Ala at position 1. Somatostatin is an endogenous neuropeptide hormone found in the brain and pancreas that inhibits the release of somatotropin. Somatostatin binds several isoforms of the somatostatin receptor, exhibiting anxiolytic, antiepileptic/anticonvulsant, and anorexigenic activities.	price>
R-M-209	[Tyr11] Somatostatin Peptide,CAS:59481-27-5	Somatostatin is an endogenous neuropeptide hormone found in the brain and pancreas. Somatostatin binds several isoforms of the somatostatin receptor, exhibiting anxiolytic, antiepileptic/anticonvulsant, and anorexigenic activities. In vivo, somatostatin improves performance in the light/dark avoidance test. Somatostatin also suppresses seizures and prevents the generation of seizures, potentially through modulation of GABA signaling. Somatostatin induces cell death under hypoxic/ischemic conditions. In tumor cells, somatostatin displays pro-apoptotic properties, potentially involving the inhibition of PI3K/Akt signaling. Somatostatin also limits food intake and inhibits secretion of insulin and glucagon through alteration of Gβγ signaling and P/Q-type N-type, and L-type voltage-gated Ca2+ channel signaling.	price>
R-M-210	[Sar9]SP	Substance P belongs to the tachykinin family which excites neurons, provoke behaviorial responses, are potent vasodilators and secretagogues.The neuropeptide substance P(SP) is a major mediator of neurogenic inflammation and immunomodulatory activities within the central and peripheral nervous system. [Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.	price>
R-M-211	[Sar1]Ang II Peptide,CAS r: 51833-69-3	[Sar1] angiotensin Ⅱ (Ang Ⅱ) can promote protein synthesis and cell growth of chicken embryonic cardiomyocytes in cell culture.Angiotensin II is the physiologically active form and regulates both the volume and the mineral balance in the body.	price>
R-M-212	[Pro9] Substance P,Cas No. 104486-69-3	Substance P belongs to the tachykinin family which excites neurons, provoke behaviorial responses, are potent vasodilators and secretagogues.Substance P(SP) is an endogenous tachykinin neuropeptide that is involved in inflammatory, pain, and stress signaling; it exhibits neuroprotective, cognition enhancing, and gastrointestinal motility modulating activities. SP exhibits neuroprotective activity by decreasing expression of Kv1.4 K+ channels in transgenic animal models of Alzheimer’s disease and improving cognitive performance in the Morris water maze task. SP is the natural ligand for the neurokinin-1 (NK1) receptor. In various animal models, SP modulates opioid signaling, induces gastric mucosal protection, and inhibits retinal apoptosis. SP also prevents hyperoxia-induced lung damage, decreasing levels of malondialdehyde and increasing levels of superoxide dismutase (SOD); this activity may be regulated through Shh signaling. In melanoma cells, SP decreases levels of tyrosinase and melanin, inhibiting melanogenesis. In other cellular models, SP increases the viability and proliferation of osteoblasts and promotes gap junction intracellular communication.	price>
R-M-213	[Nle4, D-Phe7] alpha-MSH Peptide,CAS: 75921-69-6	[Nle4, D-Phe7] alpha-MSH Peptide (melanotan I) is a synthetic analog of the naturally occurring melanocortin peptide hormone alpha-melanocyte stimulating hormone (alpha-MSH) that is an agonist for melanocortin receptors (MC1R, MC3-5R). Alpha-MSH and analogs cause melanin production in skin cells, thereby reduce UV damage by sun exposure.	price>
R-M-173	T-Peptide trifluoroacetate salt, CAS: 2022956-62-1	Peptide derived from microtubule binding repeat of Tau protein. Self-assembles into 30-55 nm paired helical filaments (PHFs) even in the absense of inducers. Cytotoxic in multiple cell lines including cortical neurons, cerebellar granular neurons, neuroblastoma cells, kidney fibroblasts and HEK293 cells. Co-localizes with pathological hyperphosphorylated forms of tau in vitro.	price>
R-M-214	[Nle11] Substance P ,cas:57462-42-7	[Nle11] Substance P,cas:57462-42-7 from ruixi.Substance P belongs to the tachykinin family which excites neurons, provoke behaviorial responses are potent vasodilators and secretagogues.Substance P(SP) is an endogenous tachykinin neuropeptide that is involved in inflammatory, pain, and stress signaling; it exhibits neuroprotective, cognition enhancing, and gastrointestinal motility modulating activities. SP exhibits neuroprotective activity by decreasing expression of Kv1.4 K+ channels in transgenic animal models of Alzheimer’s disease and improving cognitive performance in the Morris water maze task. SP is the natural ligand for the neurokinin-1 (NK1) receptor. In various animal models, SP modulates opioid signaling, induces gastric mucosal protection, and inhibits retinal apoptosis. SP also prevents hyperoxia-induced lung damage, decreasing levels of malondialdehyde and increasing levels of superoxide dismutase (SOD); this activity may be regulated through SHH signaling. In melanoma cells, SP decreases levels of tyrosinase and melanin, inhibiting melanogenesis. In other cellular models, SP increases the viability and proliferation of osteoblasts and promotes gap junction intracellular communication.	price>

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