Catalog |
name |
Description |
price |
R-C-7060 |
DSPE-Tetrazine |
DSPE-TZ(Tetrazine)is a derivative that combines tetrazine groups with DSPE lipids. Tetrazine is a molecule with special chemical properties,typically used for click chemistry reactions with cyclic olefins such as TCO. |
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R-C-7061 |
DSPE-PEG-L-Leucine |
DSPE is a hydrophobic phospholipid containing two C18 stearoyl chains that can be embedded into the hydrophobic core of liposomes or nanoparticles,enhancing carrier stability.L-leucine may mediate tumor cell uptake through amino acid transporters(such as LAT1),enhancing the delivery efficiency of chemotherapy or gene drugs. |
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R-C-5486 |
45%PC,30%PE,10%Cholesterol,10%PS,5%PI Blank liposome 100nm |
The specific composition of the liposome determines its properties and potential applications. In this case, the 45% PC and 30% PE provide structural stability to the liposome membrane, while the 10% cholesterol enhances membrane fluidity and stability. The incorporation of 10% PS can confer negative charge to the liposome surface, while the 5% PI can introduce additional functionality. |
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R-C-5487 |
45%PC(Egg yolk lecithin),30%PE,10%Cholesterol,10%PS,5%PI Blank liposome encapsulation 100NM |
The composition of the liposome remains the same as mentioned earlier, with the addition of an encapsulated payload.The encapsulation process involves incorporating the desired payload,such as drugs or genetic material, into the liposomes aqueous core or within the lipid bilayer, depending on the payloads characteristics and liposome formulation. |
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R-C-5488 |
45%PC(soy lecithin),30%PE,10%Cholesterol,10%PS,5%PIBlank liposome encapsulation100NM |
Soy lecithin is commonly utilized as a source of PC in liposome formulations due to its abundance and cost-effectiveness. The other components that make up the composition, namely PE, cholesterol, PS, and PI, remain the same as mentioned earlier.Encapsulation in this context refers to incorporating a payload, such as drugs or genetic material, into the liposomes internal aqueous core or within the lipid bilayer. The specific encapsulation method used may depend on the properties of the payload and the desired release profile. |
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R-C-7068 |
DSPE-Se-Se-PEG-PSMA |
DSPE-Se-Se-PEG-PSMA,DSPE-Se-Se-PEG complexes can introduce targeted ligands or antibodies by modifying functional groups on the surface, achieving targeted delivery to specific cells or tissues.PSMA(Prostate specific membrane antigen)is a glycoprotein located on the membrane of prostate cells,with enzymatic activity,mainly involved in cellular metabolism and signal transduction. |
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R-C-5490 |
45%PC,30%PE,10%Cholesterol,10%PS,5%PIBlank liposome encapsulation DSPE-PEG-FITC,200nm |
DSPE-PEG-FITC is a phospholipid derivative that contains a polyethylene glycol (PEG) chain attached to a fluorophore, FITC (fluorescein isothiocyanate). By encapsulating DSPE-PEG-FITC within the liposome, it becomes incorporated into the lipid bilayer or aqueous core, depending on the encapsulation method used.The liposome composition remains the same as mentioned earlier, with the addition of DSPE-PEG-FITC. DSPE-PEG is often used to improve liposome stability, increase circulation time, and provide stealth properties by imparting a hydrophilic PEG layer on the liposome surface. FITC, being a fluorophore, allows for the visualization and tracking of the liposomes. |
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R-C-5500 |
DSPE-CY5 |
DSPE-Cyanine5,1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Cyanine5 is a phospholipid derivative where a fluorescent dye called Cy5 is chemically linked to the distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) molecule. DSPE is a common component of liposomes, which are lipid-based nanoparticles often used as drug carriers or imaging agents. |
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R-C-5501 |
DSPE-PEG2000-CERVIGTGWVRC |
DSPE(1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is a phospholipid that is commonly used in the formulation of lipid-based nanoparticles such as liposomes. It provides stability and helps with the self-assembly of lipid bilayers.CERVIGTGWVRC refers to a peptide sequence that has been added to DSPE-PEG2000. This peptide sequence is derived from a protein or receptor associated with a specific target site in the body, such as a tumor or diseased tissue. |
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R-C-5502 |
DOPE-PEG-Fluor 488 |
DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine) is a phospholipid commonly used in the preparation of liposomes and lipid-based nanoparticles. It provides stability and fluidity to lipid bilayers.PEG (polyethylene glycol) is a polymer that is often added to lipid-based nanoparticles to improve their stability, solubility, and biocompatibility. Fluor 488 is a fluorescent dye that emits a green fluorescence signal. |
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