Product fluorescent-dyes-nir-ii

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Catalog	name	Description	price
R-M-5111	MHI-148-PEG2K-DOTA	MHI-148-PEG2K-DOTA from ruixi.MHI-148 is a near-infrared fluorescent dye, which can be used in tumor imaging in vivo,which was used here as the NIRF agent.	price>
R-M-5112	FD-1080 COOH	FD-1080 COOH from ruixi.FD-1080 COOH is a near infrared dye labeled reagent. This product is only for scientific research, not for human body.	price>
R-M-5121	RhB-Pluronic F-127	RhB-Pluronic F-127,Rhodamine B-Pluronic F-127 from ruixi.RhB-Pluronic F-127 is a fluorescent labeled dye reagent. This product is only used for scientific research, not for human body.	price>
R-M-2021	BDP 581/591 alkyne,CAS:2006345-34-0	BDP 581/591 alkyne is a linker of BDP which can be used in fluorescence polarization assays. The addition of the alkyne allows for it to be used in copper-catalyzed Click Chemistry reactions.	price>
R-M-2022	BDP 630/650 alkyne,CAS:2006345-38-4	BDP 630/650 alkyne is a BDP linker which can be read at the same channel as Cyanine5. It is a photostable compound and is commonly used for fluorescence polarization assays. The addition of the alkyne to the compound allows for it to be used in Click Chemistry reactions with azides.	price>
R-M-2025	Dde TAMRA Biotin Alkyne,Cas:2353409-55-7	Dde TAMRA Biotin Alkyne is a trifunctional, cleavable probe that allows for efficient recovery of avidin-bound protein complexes in affinity-based assays. This reagent contains a fluorescent dye (TAMRA) and biotin moiety linked to azide group through a spacer arm containing a hydrazine-cleavable Dde moiety. Under mild conditions (2% aqueous hydrazine), the Dde liner is cleaved, releasing the biotin tag and any avidin conjugate bound to it.	price>
R-M-5450	IR 650 NHS ester	IR 650 NHS Ester (IRDye® 650 NHS Ester analog) is a water-soluble, bright, far-red-fluorescent dye . IR 650 conjugates ideally suited for the 633 nm or 647 nm laser lines.The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling with the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with IR 650 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection. IR 650 conjugates can be used for detection of low abundance targets.	price>
R-M-5451	IR 650 Maleimide	IR 650 Maleimide (IRDye® 650 Maleimide analog) is a water-soluble, bright, far-red-fluorescent dye and is spectrally similar to other 650 dyes that are used for flow cytometry, microscopy and other applications. IR 650 conjugates ideally suited for the 633 nm or 647 nm laser lines. Maleimide is the most popular sulfhydryl-reactive reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.	price>
R-M-5452	IR 650 Azide	IR 650 Azide (IRDye® 650 Azide analog) is a water-soluble, bright, far-red-fluorescent probe with excitation ideally suited for the 633 nm or 647 nm laser lines. IR 650 Azide can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.	price>
R-M-5453	IR 650 Picolyl Azide	IR 650 Picolyl Azide (IRDye® 650 Azide analog) is an advanced fluorescent probe that incorporates a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site. The rate of CuAAC reaction depends on concentrations of all reagents, including copper, thus the raise of the effective copper concentration at the reaction site dramatically increase the rate of CuAAC reaction without the need to increase concentration of azide reagent and copper.In addition, the use of IR 650 Picolyl Azide instead of conventional IR 650 Azide allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling.In summary, the introduction of a picolyl moiety into an azide probe leads to a substantial increase in the sensitivity of alkyne detection. This will be of special value for the detection of low abundance targets or where significant increase in signal intensity is desired.	price>

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