Product phospholipids -lipids-for-drug-delivery

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Catalog	name	Description	price
R-C-7473	A2-Iso5-2DC18 CAS：2412492-07-8	A2-Iso5-2DC18 is a top-performing lipid for mRNA delivery in bone marrow-derived dendritic cells(BMDCs),BMDMs and HeLa cells.This product is only for scientific research and cannot be used on the human body.	price>
R-C-7476	244cis CAS:2956402-64-3	Di((Z)-non-2-en-1-yl)9,9-((2-(4-(9-(((Z)-non-2-en-1-yl)oxy)-9-oxononyl)piperazin-1-yl)ethyl)azanediyl)dinonanoate,244cis is a piperazine based ionizable cationic lipid used for the preparation of lipid nanoparticles(LNPs).Compared with LNPs with SM-102 content,LNPs rich in 244cis and encapsulating mRNA reporter genes specifically accumulate in mouse lungs,which can reduce the level of chemokine(C-C motif)ligand 2(CCL2)in serum.This product is only for scientific research and cannot be used on the human body.	price>
R-C-7477	CL4H6 CAS:2256087-35-9	CL4H6 is a pH-sensitive cationic lipid.CL4H6 is the main component of lipid nanoparticles(LNPs), which can be used to target and deliver siRNA,and induces a potent gene-silencing response.This product is only for scientific research and cannot be used on the human body.	price>
R-C-7561	SN38-Oleate	SN38 Oleate is a lipid derivative formed by covalent coupling of 7-ethyl-10-hydroxycamptothecin (SN38)and oleic acid through ester bonds.It is a typical long-chain fatty acid modified prodrug model compound. Its molecular structure combines the active core of SN38 with the long-chain hydrophobic alkyl group of oleic acid,with a molecular weight of approximately 562.7.It appears as a light yellow oil and is almost insoluble in water,but easily soluble in organic solvents such as chloroform and dimethyl sulfoxide.This product is only for scientific research and cannot be used on the human body.	price>
R-C-6001	4A3-SC8 CAS：1857340-78-3	4A3-SC8 is an ionizable lipid dendrimer used in generating lipid nanoparticles (LNPs) for RNA delivery. Incorporation of differently charged lipids (DODAP, DOTAP, or PA) into 4A3-SC8 LNPs allow for selective delivery of RNA to the liver,lungs,or spleen.The product is only suitable for scientific research experiments and is not intended for human or clinical use.	price>
R-C-6006	AA3-DLin CAS：2832061-33-1	AA3-DLin is an ionizable lipid used in generating lipid nanoparticles(LNPs)for RNA delivery.Unlike LNPs formulated with other ionizable lipids,AA3-DLin LNPs performed best with higher proportions of phospholipid and lower cholesterol(40:40:25:0.5 AA3-DLin/DOPE/cholesterol/DMG-PEG).AA3-DLin containing LNPs were able to deliver full-length SARS-COV2 spike protein mRNA to BALB/c mice and generate a strong immune response.The product is only suitable for scientific research experiments and is not intended for human or clinical use.	price>
R-C-6007	ALC-0159 1849616-42-7	ALC-0159 is a PEG/lipid conjugate(PEGylated lipid),specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid,O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide).It is a non-ionic surfactant by its nature.The product is only suitable for scientific research experiments and is not intended for human or clinical use.	price>
R-C-6013	ATX100 CAS：2230647-37-5	ATX100 is a biodegradable ionizable lipid with improved in vivo activities for siRNA delivery via lipid nanoparticles(LNP).The physicochemical parameters of ATX100: pKa 6.316,lipophilicity cLogD 14.03, nanoparticle size 82nm.The product is only suitable for scientific research experiments and is not intended for human or clinical use.	price>
R-C-7712	Blank liposomes 50nm	Blank Liposomes are a type of spherical bilayer nano or micro particles formed by self-assembly of phospholipid molecules, with a hollow structure inside and no drugs or active ingredients. They are the basic materials of drug delivery systems.	price>
R-C-7713	Blank liposomes 200nm	Blank Liposomes are a type of spherical bilayer nano or micro particles formed by self-assembly of phospholipid molecules, with a hollow structure inside and no drugs or active ingredients. They are the basic materials of drug delivery systems.	price>

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