Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-2884	Human PTHrP-(1-36) CAS No.172867-62-8	Human PTHrP-(1-36)/CAS No.172867-62-8 is a secretory form of PTHrP with anticalciuric effects. Human PTHrP-(1-36) enhances beta cell function and proliferation. Human PTHrP-(1-36) can be used in the research of humoral hypercalcemia of malignancy (HHM) and hyperparathyroidism.	price>
R-R-2885	Secretin (33-59), rat TFA	Secretin (33-59), rat (TFA) is a 27-aa peptide, which acts on secretin receptor, and enhances the secretion of bicarbonate, enzymes, and K+ from the pancreas.	price>
R-R-2886	NKH477 CAS No.138605-00-2	NKH477 (Colforsin dapropate hydrochloride)/CAS No.138605-00-2 directly activates the catalytic unit of adenylate cyclase and increases intracellular cAMP. NKH477 is a forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 exerts an antiproliferative effect in vivo with an altered cytokine profile to inhibit the acute rejection of rat orthotopic lung allografts.	price>
R-R-2887	KH7 CAS No.330676-02-3	KH7/CAS No.330676-02-3 is a specific double adenyl cyclone (sAC) inhibitor, with IC50s of 3-10 μM toward both purified human sACT recombinant proteins and highly expressed sACT terolog in cellular assays KH7 is also a cAMP inhibitor	price>
R-R-2888	LRE1 CAS No.1252362-53-0	LRE1/CAS No.1252362-53-0 is a specific and allosteric inhibitor of soluble adenylyl cyclase.	price>
R-R-2889	TDI-10229 CAS No.2810887-45-5	TDI-10229/CAS No.2810887-45-5 is a potent and orally bioavailable inhibitor of soluble adenylyl cyclase (sAC, ADCY10). TDI-10229 displays nanomolar inhibition of sAC in both biochemical and cellular assays (IC50 of 195 nM) and exhibits mouse pharmacokinetic properties sufficient to warrant its use as an in vivo tool compound.	price>
R-R-2890	Fipexide CAS No.34161-24-5	Fipexide/CAS No.34161-24-5, a parachloro-phenossiacetic acid derivative, is an orally active nootropic agent. Fipexide reduces striatal adenylate cyclase activity. Fipexide has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide is used for senile dementia research. Fipexide acts as a chemical inducer in callus formation, shoot regeneration and Agrobacterium infection.	price>
R-R-2891	SKF-83566 CAS No.99295-33-7	SKF-83566/CAS No.99295-33-7 is a potent, blood-brain permeable and orally active D1-like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5-HT2 receptor (Ki=11 nM). SKF-83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5.7 μM. SKF-83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta.	price>
R-R-2892	ST034307 CAS No.133406-29-8	ST034307/CAS No.133406-29-8 is a potent and selective adenylyl cyclase 1 (AC1) inhibitor, with IC50 of 2.3 μM.	price>
R-R-2893	NKY80 CAS No.299442-43-6	NKY80/CAS No.299442-43-6 is a potent, selective and non-competitive adenylyl cyclase (AC) type V isoform inhibitor with IC50s of 8.3 µM, 132 µM and 1.7 mM for type V, III and II, respectively. NKY80 is a non-nucleoside quinazolinone and regulates the AC catalytic activity in heart and lung tissues.	price>

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