Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-2829	Survodutide CAS No.2805997-46-8	Survodutide (BI 456906)/CAS No.2805997-46-8 is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake.	price>
R-R-2830	Glepaglutide acetate	Glepaglutide (ZP1848) acetate, a long-acting GLP-2 analogue, is a potent GLP-2R agonist. Glepaglutide acetate reduces faecal output and increases intestinal absorption. Glepaglutide acetate alleviates small intestinal inflammation.	price>
R-R-2831	GLP-2(3-33) CAS No.275801-62-2	GLP-2(3-33)/CAS No.275801-62-2, generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).	price>
R-R-2832	Glucagon receptor antagonists-3 CAS No.202917-17-7	Glucagon receptor antagonists-3/CAS No.202917-17-7 is a highly potent glucagon receptor antagonist.	price>
R-R-2833	Mazdutide CAS No.2259884-03-0	Mazdutide (IBI-362; LY-3305677)/CAS No.2259884-03-0 is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide (GLP-1R) and?glucagon receptor?(GCGR). Mazdutide binds human and mouse?GCGR?(Ki: 17.7 nM and 15.9 nM, respectively) and GLP-1R (Ki: 28.6 nM and 25.1 nM, respectively) and stimulates?insulin?secretion from mouse islets (EC50: 5.2 nM). Mazdutide is used in studies of obesity and type 2 diabetes (T2D).	price>
R-R-2834	L-168049 CAS No.191034-25-0	L-168049/CAS No.191034-25-0 is a potent, selective, orally active and non-competitive glucagon receptor antagonist with IC50s of 3.7 nM, 63 nM, and 60 nM for human, murine, and canine glucagon receptors, respectively.	price>
R-R-2835	Shanzhiside methyl ester CAS No.64421-28-9	Shanzhiside methy lester/CAS No.64421-28-9 is isolated from lamiophlomis rotata. Shanzhiside methyl ester is a small molecule glucagon-like peptide-1 (GLP-1) receptor agonist and has the ability to induce anti-allodynic tolerance.	price>
R-R-2836	VU0453379 hydrochloride	VU0453379 hydrochloride is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R) with an EC50 of 1.3 μM.	price>
R-R-2837	GLP-1(7-36), amide TFA	GLP-1(7-36), amide TFA is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.	price>
R-R-2838	Dapiglutide CAS No.2296814-85-0	Dapiglutide (ZP7570)/CAS No.2296814-85-0 is a long-acting glucagon-like peptide-1 receptor 1R (GLP-1R)/Glucagon-like peptide-2 receptor (GLP-2R) dual agonist. Dapiglutide can be used for short bowel syndrome (SBS) research.	price>

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