Product peptide-drug-peptides

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Catalog	name	Description	price
R-M-1501	GLUCAGON-LIKE PEPTIDE I (7-37),Cas: 106612-94-6	Glucagon-like peptide 1 (GLP-1) is an endogenous peptide hormone that binds GLP-1 receptors, increasing cAMP and insulin secretion. GLP-1 primarily exhibits anorexigenic, anti-diabetic, and gastrointestinal modulatory activities. GLP-1 decreases food intake and glucagon levels in animal models and also slows gastric emptying. In subjects with type 2 diabetes, the response of GLP-1 to glucose is impaired and subjects show abnormally low levels of GLPs.	price>
R-M-1503	GLUCAGON-LIKE PEPTIDE II, HUMAN,Cas: 99120-49-7	Glucagon-like peptide 2 (GLP-2) is an endogenous peptide hormone primarily synthesized in the intestine and pancreas. GLP-2 binds and activates the GLP-2 receptor, exhibiting vasodilatory, antihypertensive, antidepressant, and gastrointestinal motility modulating activities. In animal models, GLP-2 increases intestinal blood flow and decreases mean arterial blood pressure. GLP-2 potentiates L-type voltage-gated Ca2+ channels through a mechanism that involves activation of PKA. Additionally, GLP-2 decreases immobility time in animals undergoing the forced swim test. This peptide stimulates cell proliferation, inhibiting chemotherapy-induced mucosal atrophy in the intestines. GLP-2 also decreases gastric emptying and gastrointestinal motility.	price>
R-M-1504	GLUCAGON-LIKE PEPTIDE II, RAT,Cas :195262-56-7	Glucagon-like peptide 2 (GLP-2) is an endogenous peptide hormone primarily synthesized in the intestine and pancreas. GLP-2 binds and activates the GLP-2 receptor, exhibiting vasodilatory, antihypertensive, antidepressant, and gastrointestinal motility modulating activities. In animal models, GLP-2 increases intestinal blood flow and decreases mean arterial blood pressure. GLP-2 potentiates L-type voltage-gated Ca2+ channels through a mechanism that involves activation of PKA. Additionally, GLP-2 decreases immobility time in animals undergoing the forced swim test. This peptide stimulates cell proliferation, inhibiting chemotherapy-induced mucosal atrophy in the intestines. GLP-2 also decreases gastric emptying and gastrointestinal motility.	price>
R-M-1506	HELODERMIN,Cas:89468-62-2	Helodermin is a peptide originally found in Heloderma lizards. Helodermin exhibits vasodilatory and antihypertensive activities, decreasing blood pressure in vivo; this arterial relaxation is accompanied by a decrease in intracellular Ca2+ and an increase in cAMP. Helodermin may also exhibit anticancer benefit, inhibiting cell proliferation of small cell lung cancer (SCLC) cells in vitro.	price>
R-M-1507	HELOSPECTIN I,Cas :93438-37-0	Helospectin I is a peptide originally found in Heloderma lizards. Helospectin I is a neuropeptide of the vasoactive intestinal peptide (VIP) family that exhibits vasodilatory and antihypertensive activities, decreasing blood pressure in vivo. Additionally, helospectin I increases plasma glucagon in animal models.	price>
R-M-1508	HELOSPECTIN II,Cas:93585-83-2	Helospectin II is a peptide originally found in Heloderma lizards. Helospectin II is a neuropeptide of the vasoactive intestinal peptide (VIP) family that exhibits vasodilatory and antihypertensive activities, decreasing blood pressure in vivo.	price>
R-M-1510	PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (6-27), HUMAN, SHEEP, RAT	Pituitary adenylate cyclase-activating polypeptide (PACAP) is an endogenous peptide that stimulates cAMP production in the anterior pituitary. PACAP and PACAP-related peptide (PRP) regulate immune function and display increases in expression when hosts are challenged with bacterial pathogens. PACAP and PRP also control expression of reproductive hormones such as follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Additionally, PACAP and PRP bind the PAC1 receptor and VPAC1/2 receptors. PACAP itself inhibits K+ amplitude of delayed rectifier K+ channels, exhibiting anti-apoptotic activity in cerebellar granule cells.	price>
R-M-1511	PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE-RELATED PEPTIDE, HUMAN	Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates cAMP production in the anterior pituitary. PACAP and PACAP-related peptide (PRP) regulate immune function and display increases in expression when hosts are challenged with bacterial pathogens. PACAP and PRP also control expression of reproductive hormones such as follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Additionally, PACAP and PRP bind the PAC1 receptor and VPAC1/2 receptors. PACAP itself inhibits K+ amplitude of delayed rectifier K+ channels, exhibiting anti-apoptotic activity in cerebellar granule cells.	price>
R-M-1513	SECRETIN, PIG,Cas:17034-35-4	Secretin is an endogenous peptide hormone involved in digestion and feeding behavior; it binds to its own GPCR secretin receptor (SCTR). In adipocytes, secretin stimulates lipolysis, mediated by PKA and hormone-sensitive lipase (HSL) signaling; it also induces uptake of fatty acids and secretion of MCP-1 and adiponectin. Secretin enhances ambulation distance but not exploratory activity in animal models of repetitive hyperactivity. Additionally, secretin increases expression of tyrosine hydroxylase, stimulating catecholamine secretion in PC12 neurons.	price>
R-M-1575	alpha-Casein (90-95),CAS:83471-50-5	The alpha-casein was the most potent opioid in opioid activity bioassays.	price>

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