SECRETIN, PIG,Cas:17034-35-4

Secretin is an endogenous peptide hormone involved in digestion and feeding behavior; it binds to its own GPCR secretin receptor (SCTR). In adipocytes, secretin stimulates lipolysis, mediated by PKA and hormone-sensitive lipase (HSL) signaling; it also induces uptake of fatty acids and secretion of MCP-1 and adiponectin. Secretin enhances ambulation distance but not exploratory activity in animal models of repetitive hyperactivity. Additionally, secretin increases expression of tyrosine hydroxylase, stimulating catecholamine secretion in PC12 neurons.

msds of SECRETIN, PIG