Product fluorescent-dyes-coumarin

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Catalog	name	Description	price
R-M-5401	7-AMCA NHS ester,cas:113721-87-2	AMCA NHS Ester (succinimydyl-7-amino-4-methylcoumarin-3-acetic acid) is one of the most popular blue fluorescent tagging molecules. It is widely used to label antibodies, proteins and small drug molecules. Often used as contrasting probes for double- and triple-labeling in immunofluorescence microscopy, arrays and in situ hybridization. The desirable properties of AMCA dyes include a relatively large Stoke’s shift and resistance to photobleaching.	price>
R-M-5402	7-AMCA maleimide	7-amca dye is a very common dye. It is a coumarin dye excited by UV and emitting blue fluorescence (ex/em ~ 353/442). It can be used in combination with the fluorescence of various other colors. Like other blue fluorescent dyes, AMCA fluorescence is not very bright and is only suitable for target dyeing with high abundance.Maleimide is a group commonly used in biomarker reaction. It can generate stable thioether structure through affinity addition reaction with sulfhydryl (- SH), so as to realize labeling. Although amino groups (such as lysine arginine side chain) also have affinity, maleimide selectively labels sulfhydryl groups in neutral or slightly acidic buffer (reaction speed > 1000 times faster than amino groups). The labeling reaction has the advantages of rapid reaction, high selectivity and good yield. In addition, sulfhydryl is a functional group widely existing in biomolecules, such as serine and disulfide bond in proteins. Therefore, maleimide / thiol labeling has become the most commonly used biological ligation reaction second only to NHS / amino labeling.	price>
R-M-5403	Coumarin 343 PEG2 azide	Coumarin 343 PEG2 azide,Coumarin 343 polyethylene glycol2 azide from ruixi.Coumarin 343 is one of the coumarin series dyes. It emits blue fluorescence with an emission peak of about 480 nm. This dye is often paired with fluorescein to form FRET pair. Coumarin 343 PEG2 azide can have click chemistry reaction with alkynes or tension alkynes to form stable conjugates and realize the biomarker of coumarin 343. There is a short chain peg arm between azide and coumarin 343 dye, which can improve the labeling efficiency and the water solubility of the dye.	price>
R-M1-8883	Coumarin-urokinase	Coumarin-urokinase is likely a fusion protein or conjugate where the proteolytic enzyme urokinase is linked to a coumarin molecule. Urokinase is a serine protease that plays a role in the breakdown of blood clots, and coumarin is a fluorescent compound commonly used as a fluorescence tracer or label in biological research.When urokinase is linked to coumarin, it can serve as a tool for studying the activity, localization, and behavior of urokinase in biological systems. The fluorescent property of coumarin allows for the visualization and tracking of the urokinase enzyme, enabling researchers to study its distribution, activity, and interactions.	price>
R-M-5437	AMCA LC Acid	AMCA (7-amino-4-methyl-3-coumarinacetic acid) is a blue fluorescent dye that is a non - sulfonated version of the Alexa Fluor® 350 dye. It is often used as a contrasting probe for double - and triple - labeling in immunofluorescence microscopy, arrays, and in situ hybridization. The desirable properties of AMCA dyes include a relatively large Stoke’s shift and resistance to photobleaching.(AMCA LC Acid）This reagent is supplied as Boc protected derivative to ensure compatibility with Fmoc solid phase peptide synthesis. Medium length, hydrophobic spacer arm (total length is 22.4 angstroms) provides an adequate separation between the dye and peptide. Spacers of different lengths are available upon request.	price>
R-M-5439	Fmoc Lys(AMCA)-OH	AMCA (7-amino-4-methyl-3-coumarinacetic acid) is a blue fluorescent dye that is a non-sulfonated version of the Alexa Fluor® 350 dye. It is often used as a contrasting probe for double - and triple - labeling in immunofluorescence microscopy, arrays, and in situ hybridization. The desirable properties of AMCA dyes include a relatively large Stoke’s shift and resistance to photobleaching.Fmoc Lys(AMCA) OH is a building block for in-sequence peptide labeling by AMCA dye. It allows incorporation of fluorescent tag into a peptide chain using standard Fmoc peptide solid phase synthesis. This reagent is supplied as Boc protected derivative to ensure compatibility with Fmoc solid phase peptide synthesis. Spacers of different lengths are available upon request.	price>
R-M-5442	6,8-Difluoro-7-hydroxy-4-methylcoumarin NHS Ester	6,8-Difluoro-7-hydroxy-4-methylcoumarin NHS Ester exhibit bright blue fluorescence emission near 460 nm is optimally excited by the intense 365 nm spectra line of the mercury-arc lamp and detect optimally with DAPI optical filter sets. 6,8-Difluoro-7-hydroxy-4-methylcoumarin NHS Ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a stable, covalent amide bond. The NHS ester (or succinimidyl ester) is the most popular tool for conjugating dyes to the primary amines of protein or antibody (Lys), amine-modified oligonucleotides, and other amine-containing molecules.	price>
R-M-5443	Difluorocarboxyfluorescein NHS Ester, 6-isomer	Difluorocarboxyfluorescein NHS Ester, 6-isomer (also known as Oregon Green™ 488 Carboxylic Acid, Succinimidyl Ester, 6-isomer) is an amine-reactive fluorinated analog of fluorescein that overcomes some of the key limitations of fluorescein, including greater photostability and a lower pKa (pKa ~ 4.7 versus 6.4 for fluorescein), making its fluorescence essentially pH insensitive in the physiological pH range.Difluorocarboxyfluorescein NHS Ester, is a preferred, routinely used fluorescent dye for labeling proteins, peptides and nucleotides.	price>
R-M-5636	7-ethoxy-4-Methylcoumarin,cas:87-05-8	7-ethoxy-4-Methylcoumarin is a fluorophore used to monitor functional activity of cytochrome P450 (CYP)1A1, CYP2B4, and CYP2B6.	price>
R-M-5656	7-Amino-4-chloromethylcoumarin,cas:147963-22-2	7-Amino-4-chloromethylcoumarin is a thiol-reactive, cell-permeant, fluorescent probe that is commonly used as a long-term cell tracer. It is well retained in cells for at least 24 hours.	price>

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