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Catalog	name	Description	price
R-M-1437	Big Endothelin 1 [1-38] Peptide	Endothelins are endothelium-derived vasoconstrictor peptides. Endothelin-1 is expressed as a 212-aa precursor (preproendothelin-1) that is sequentially cleaved into 2 chains: Endothelin-1 (21 aa) and Big Endothelin-1 (38 aa). Big endothelin-1 is cleaved to yield endothelin-1 via the activity of an endothelin-converting enzyme (ECE). Big Endothelin-1 can be hydrolyzed by chymase to generate endothelin 1 (1-21) in vitro.	price>
R-M-1448	Beta Casomorphin 1-4 Peptide (Bovine),cas:74171-19-0	Beta Casomorphin 1-4 Peptide (Bovine) corresponds to aa75-78 of bovine beta casein sequence. Casomorphins are bioactive peptides derived from the digestion of beta-casein, a milk protein, with a role in micelle formation. There are associations between serum levels of beta-casomorphins and risk of sudden infant death syndrome, histamine release, stimulation of food intake, and lymphocytosis.	price>
R-M-1449	Beta Casomorphin 1-3 Peptide,Cas:72122-59-9	Beta Casomorphin 1-3 Peptide corresponds to aa66-68 of human beta casein sequence and is conserved with the bovine sequence. Casomorphins are bioactive peptides derived from the digestion of beta-casein, a milk protein, with a role in micelle formation. There are associations between serum levels of beta-casomorphins and risk of sudden infant death syndrome, histamine release, stimulation of food intake, and lymphocytosis.	price>
R-M-1471	[SAR1 ILE8]-ANGIOTENSIN II,Cas:37827-06-8	Angiotensin II (AT II) is a peptide produced from AT I by angiotensin-converting-enzyme (ACE). AT II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels; this results in contraction and vasoconstriction, increasing blood pressure. AT II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney. Here, AT II increases reabsorption of Na+ and HCO3- and excretion of H+, increasing blood volume and pH and further increasing blood pressure.	price>
R-M-1487	TUFTSIN,CAS:9063-57-4	Tuftsin is a tetrapeptide that binds the neuropilin-1 (Nrp1) receptor, modulating TGF-β, cGMP, and Ca2+ signaling. Tuftsin is derived from the Fc region of IgG. Tuftsin exhibits immunomodulatory activity, inducing leukocytes to become cytotoxic effector cells and stimulating phagocytosis in macrophages and microglia in cellular models. Tuftsin also displays anticancer chemotherapeutic benefit, enhancing the effects of co-administered chemotherapeutic compounds. In animal models, tuftsin also inhibits withdrawal-associated behaviors.	price>
R-M-1489	ADRENOMEDULLIN (1-52), HUMAN,Cas : 148498-78-6	Adrenomedullin is an endogenous peptide hormone involved in growth and differentiation of stem cells. This peptide exhibits vasodilatory, natriuretic, and cardioprotective activities. Adrenomedullin decreases blood pressure and increases neovascularization. This peptide binds microtubule-associated proteins in the cytoskeleton and also activates CLR-RAMP receptors, regulating vascular tone and cardiovascular development.	price>
R-M-1505	GLUCAGON, HUMAN,Cas :16941-32-5	Glucagon is an endogenous pancreatic peptide hormone that binds glucagon receptors to increase glucose levels and counteract the effects of insulin. Glucagon is clinically used to treat severe hypoglycemia and anaphylactic shock. Glucagon exhibits some antihypertensive activity, decreasing blood pressure.	price>
R-M-1514	SINCALIDE,Cas :25126-32-3	Sincalide is an octapeptide fragment of cholestocystokinin (CCK) that activates the CCK receptor on immune cell surfaces. Sincalide is more potent when sulfated. Sincalide exhibits neuroprotective, immunosuppressive, and anorexigenic activities. In hippocampal neurons, sincalide increases the density of filopodia and dendritic spines. In vagal motor neurons, sincalide increases excitatory currents. In other cellular models, this compound inhibits IgG1 production and regulates transcription factor expression and activation of B cells. Sincalide also modulates hormone signaling, increasing adrenocorticotropic hormone (ACTH) secretion and altering leptin, melanocortin, and corticotropin-releasing factor (CRF) pathways. In separate animal models, sincalide decreases appetite and increases cardiac output, also increasing gastrointestinal blood flow.	price>
R-M-1517	MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55), RAT,Cas :163913-87-9	Myelin oligodendrocyte glycoprotein (35-55) is a peptide used to induce experimental autoimmune encephalitis (EAE) via immunization; it is an antigen that induces an immune response against myelin designed to mimic conditions of multiple sclerosis.	price>
R-M-1578	Angiotensinogen (1-14), human,CAS :104180-23-6	Angiotensinogen (1-14), human,CAS :104180-23-6 from ruixi.Angiotensinogen is a serum globulin formed by the liver that is cleaved by renin to form angiotensin I. Angiotensinogen is also called angiotensin precursor.	price>

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