Product apis-apoptosis

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Catalog	name	Description	price
R-R-1896	Conophylline CAS No.142741-24-0	Conophylline/CAS No.142741-24-0 is a vinca alkaloid extracted from leaves of a tropical plant Ervatamia microphylla. Conophylline is a differentiation inducer of for pancreatic cells. Conophylline suppresses HSC and induces apoptosis.	price>
R-R-1897	Corosolic acid CAS No.4547-24-4	Corosolic acid (Colosolic acid)/CAS No.4547-24-4 isolated from the fruit of Cratoegus pinnatifida var. psilosa, was reported to have anticancer activity. Corosolic acid induces cancer cell apoptosis.	price>
R-R-1898	Liensinine perchlorate CAS No.2385-63-9	Liensinine Perchlorate/CAS No.2385-63-9 is a constituent of Nelumbo nucifera Gaertn, with ani-hypertension and anti-cancer activities. Liensinine Perchlorate induces colorectal cancer (CRC) cell apoptosis.	price>
R-R-1899	Genistein 8-c-glucoside CAS No.66026-80-0	Genistein 8-c-glucoside (G8CG)/CAS No.66026-80-0 is a glucoside. Genistein 8-c-glucoside induces mitochondrial membrane depolarization and induces apoptosis.	price>
R-R-1900	WEHI-9625 CAS No.2595314-46-6	WEHI-9625/CAS No.2595314-46-6 is a tricyclic sulfone, first-in-class inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK. WEHI-9625 is completely inactive against both human BAK and the closely related apoptosis effector BAX.	price>
R-R-1901	Fraxetin CAS No.574-84-5	Fraxetin/CAS No.574-84-5 is isolated from Fraxinus rhynchophylla Hance. Fraxetin has antitumor, anti-oxidation effects and anti-inflammory effects. Fraxetin induces apoptosis.	price>
R-R-1902	Supinoxin CAS No.888478-45-3	Supinoxin (RX-5902)/CAS No.888478-45-3 is an orally active inhibitor of phosphorylated-p68 RNA helicase (P-p68) and a potent first-in-class anti-cancer agent. Supinoxin interacts with Y593 phosphorylated-p68 and attenuates the nuclear shuttling of β-catenin. Supinoxin induces cell apoptosis and inhibits growth of TNBC cancer cell lines with IC50s ranging from 10 nM to 20 nM.	price>
R-R-1903	KS106 CAS No.2408477-50-7	KS106/CAS No.2408477-50-7 is a potent ALDH inhibitor with IC50s of 334, 2137, 360 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively. KS106 shows antiproliferative and anticancer effects with low low toxic.KS106 significantly increases ROS activity, lipid peroxidation and toxic aldehyde accumulation. KS106 induces apoptosis and cell cycle arrest at the G2/M phase.	price>
R-R-1904	CNDAC hydrochloride CAS No.134665-72-8	CNDAC hydrochloride/CAS No.134665-72-8 is a metabolite of the orally active agent Sapacitabine (HY-16445), and a nucleoside analog. CNDAC hydrochloride induces DNA damage and apoptosis.	price>
R-R-1905	Minnelide CAS No.1254702-87-8	Minnelide/CAS No.1254702-87-8 is a prodrug of triptolide that shows potent antitumor activity in a number of tumor types, particularly in pancreatic cancer. Minnelide promotes apoptosis.	price>

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