Product apis-apoptosis

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Catalog	name	Description	price
R-R-1866	Erasin	Erasin is a potent Erlotinib (HY-50896)-resistance antagonizing STAT3 inhibitor with IC50s of 9.7 and 24 μM against STAT3 and STAT1, respectively. Erasin induces cancer cells apoptosis.	price>
R-R-1867	ROC-325 CAS No.1859141-26-6	ROC-325/CAS No.1859141-26-6 is a potent and orally active autophagy inhibitor with a strong anticancer activity. ROC-325 induces the deacidification of lysosomes, accumulation of autophagosomes, and disrupted autophagic flux. ROC-325 also induces renal cell carcinoma apoptosis.	price>
R-R-1868	Bioymifi CAS No.1420071-30-2	Bioymifi (DR5 Activator)/CAS No.1420071-30-2, a potent TRAIL receptor DR5 activator, binds to the extracellular domain (ECD) of DR5 with a Kd of 1.2 μM. Bioymifi can act as a single agent to induce DR5 clustering and aggregation, leading to apoptosis.	price>
R-R-1869	Milademetan tosylate hydrate CAS No.2095625-97-9	Milademetan (DS-3032) tosylate hydrate/CAS No.2095625-97-9 is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) tosylate hydrate induces G1 cell cycle arrest, senescence and apoptosis.	price>
R-R-1870	Oxythiamine CAS No.136-16-3	Oxythiamine (Hydroxythiamin)/CAS No.136-16-3, an analogue of anti-metabolite, can suppress the non-oxidative synthesis of ribose and induce cell apoptosis. Oxythiamine is a thiamine antagonist and inhibits transketolase (TK). Oxythiamine inhibits cancer cell apoptosis and inhibits cell proliferation.	price>
R-R-1871	MARK4 inhibitor 1 CAS No.2271081-58-2	MARK4 inhibitor 1/CAS No.2271081-58-2 is a potent and selective microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM. MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis.	price>
R-R-1872	RKI-1447 dihydrochloride CAS No.1782109-09-4	RKI 1447 dihydrochloride/CAS No.1782109-09-4 is a potent and selective ROCK inhibitor with IC50s of 14.5 and 6.2 nM for ROCK1 and ROCK2, respectively. RKI 1447 dihydrochloride suppresses colorectal carcinoma cell growth and promotes apoptosis.	price>
R-R-1873	Glycochenodeoxycholic acid-d4 CAS No.1201918-16-2	Glycochenodeoxycholic acid-d4/CAS No.1201918-16-2 is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis.	price>
R-R-1874	Tubulin inhibitor 1 CAS No.2237054-53-2	Tubulin inhibitor 1/CAS No.2237054-53-2 is a tubulin inhibitor, inhibits tubulin polymerization. Tubulin inhibitor 1 shows potent anti-tumor activity, casues cellular mitotic arrest in the G2/M phase, and induces cellular apoptosis.	price>
R-R-1875	Isoalantolactone CAS No.470-17-7	Isoalantolactone/CAS No.470-17-7 is an apoptosis inducer, which also acts as an alkylating agent.	price>

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