Product peptide-Inhibitory-peptide

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Catalog	name	Description	price
R-M-986	Myristoyl-Lys-Arg-Thr-Leu-Arg-OH,CAS :125678-68-4	The myristylated pentapeptide Myr-KRTLR is an effective inhibitor of the protein kinase C (PKC)-catalyzed histone phosphorylation (inhibitory constant, IC₅₀ = 75 µM). It competes with the phosphoacceptor substrate of PKC and interacts with the phospholipid cofactor of the enzyme.	price>
R-M-987	Myristoyl-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-OH trifluoroacetate salt,CAS : 147217-25-2	The myristoylated nonapeptide Myr-FARKGALRQ corresponding to the pseudosubstrate domain of PKC-α and -β subtypes represents a selective and cell-permeable inhibitor of PKC in intact cells.	price>
R-M-997	Neural-Cadherin (76-85) amide (chicken),CAS:127650-08-2	This decapeptide resides within the first extracellular domain (EC1) of N-cadherin. It inhibits cadherin-mediated cell adhesion, compaction of eight-cell-stage mouse embryos and rat neurite outgrowth on astrocytes. In the presence of this peptide Ca²⁺-dependent cell aggregation of bovine brain microvessel endothelial cells is prevented. A putative application in creating channels for paracellular drug delivery across blood brain barriers has been proposed.	price>
R-M-1013	Neuropeptide EI (human, mouse, rat) trifluoroacetate salt,CAS:125934-45-4	NEI (neuropeptide EI) is processed from pro-MCH. It has been reported that rat MCH may act as a central corticotropin inhibitory factor involved in the circadian rhythmicity of plasma ACTH levels in the rat while NEI antagonizes its action.	price>
R-M-1025	Neuropeptide Y (1-24) amide (human, rat) trifluoroacetate salt,CAS: 131448-51-6	NPY fragment with slight antagonistic effects on NPY-induced inhibition of the vas deferens response to electrical stimulation.	price>
R-M-1020	NFAT Inhibitor trifluoroacetate salt,CAS:249537-73-3	The high-affinity calcineurin-binding peptide potently inhibited NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells, without affecting the expression of other cytokines that require calcineurin but not NFAT. NFAT inhibitors may be useful in treating chronic ailments such as myocardial hypertrophy, allergy, arthritis, and autoimmune disease.	price>
R-M-1024	Nuclear Factor NF-KB Inhibitor SN50 trifluoroacetate salt,CAS: 213546-53-3	Nuclear Factor NF-KB Inhibitor SN50 is a cell-permeable nuclear translocation inhibitor of the transcription factor NF-KB.The peptide inhibited nuclear translocation of NF-KB in LPS- or TNF-α-stimulated murine endothelial LE-II and human monocytic THP-1 cells. In several cell lines SN50 interfered with NF-KB-mediated pro-apoptotic events such as caspase-3 activation.	price>
R-M-1069	OM99-2 trifluoroacetate salt,CAS : 314266-76-7	OM99-2, EVNL-psi[CHOH-CH₂]-AAEF-NH₂, is a potent inhibitor for human brain memapsin-2 (β-secretase) containing a Leu-Ala hydroxyethylene isostere with a Ki-value of 9.58 · 10⁻⁹ M.	price>
R-M-1086	PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) trifluoroacetate salt	The PACAP selective antagonist PACAP (6-38) is a potent and selective inhibitor of PACAP-27-stimulated pituitary adenylate cyclase with a Ki values of 150 nM.	price>
R-M-1107	Pepstatin A,CAS:26305-03-3	Pepstatin A (isovaleryl-pepstatin), a low molecular weight inhibitor of acid proteases, e.g. pepsin, renin, cathepsin D, and plasmepsin II. For the Plasmodium falciparum aspartyl protease plasmepsin II, Hill et al determined an IC₅₀ of 0.1 nM.	price>

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