Catalog |
name |
Description |
price |
R-M-669 |
Diprotin A |
Diprotin A,CAS :90614-48-5 is an inhibitor of dipeptidyl aminopeptidase IV. |
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R-M-672 |
Dolastatin 15 |
Dolastatin 15 belongs to a family of antimitotic and antineoplastic depsipeptides inducing apoptosis in various malignant cell types. It was shown to inhibit the growth of the P388 lymphocytic leukemia cell line efficiently, with an ED₅₀ value of 2.4 ng/mL.
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R-M-685 |
Echistatin,CAS:154303-05-6 |
Echistatin is a 49-amino acid polypeptide from the venom of the saw-scaled viper, Echis carinatus. The peptide containing an RGD motif binds to the glycoprotein IIb/IIIa receptor on the platelet and is a potent competitive inhibitor of ADPstimulated platelet aggregation mediated by fibrinogen and other factors. Furthermore, echistatin effectively inhibits osteoclastic bone resorption in vitro and in vivo. |
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R-M-479 |
Abz-Ser-Pro-3-nitro-Tyr-OH |
Abz-Ser-Pro-3-nitro-Tyr-OH (CAS# 553644-01-2) is a useful research chemical compound.Selective substrate for angiotensin-converting enzyme 2 (ACE2), an ACE homolog which differs in its specificity and physiological role from ACE.The internally quenched fluorescent (FRET) substrate is potentially useful in applications such as high-throughput screening of ACE2 inhibitors. |
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R-M-701 |
Brain-Derived Neurotrophic Factor (human) |
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family. Its expression in the human central nervous system is altered in neurodegenerative diseases like Alzheimer and Parkinson disease. BDNF promotes survival of dopaminergic neurons and protects against Aβ-induced neurotoxicity in vitro and in vivo. |
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R-M-485 |
Ac-Ala-Leu-Cys-Asp-Asp-Pro-Arg-Val-Asp-Arg-Trp-Tyr-Cys-Gln-Phe-Val-Glu-Gly-NH₂ (Disulfide bond) |
The potent anticoagulant E-76, Acetyl-ALCDDPRVDRWYCQFVEG-amide, is an inhibitor of coagulation factor VIIa. It has been suggested that E-76 works by binding to an exosite on the factor VIIa protease domain, and non-competitively inhibits activation of factor X and amidolytic activity. E-76 has a well defined structure in solution determined by NMR spectroscopy that is similar to the X-ray crystal structure when complexed with factor VIIa and represents a new framework for the development of inhibitors for serine proteases. |
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R-M-703 |
Astressin trifluoroacetate salt |
Astressin trifluoroacetate salt ,CAS: 170809-51-5 from ruixi.The Glu³⁰ to Lys³³ lactam bridge constrains astressin in an α-helical conformation which seems to be responsible for its especially high CRF antagonist activity. Astressin is 100 times more potent than α-helical CRF (9-41) at inhibiting ACTH secretion in vitro, and more than 10 times more potent in vivo than any other CRF antagonist reported to date. |
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R-M-731 |
Calpain Inhibitor II |
Calpain Inhibitor II ,ALLM from ruixi.Ac-LLM-CHO (ALLM) is a potent competitive inhibitor of cathepsin L (Ki=0.6 nM) and cathepsin B (Ki=100 nM). |
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R-M-734 |
cAMP-Dependent Protein Kinase Inhibitor-α (5-22) amide (human, mouse, rabbit, rat) |
cAMP-Dependent Protein Kinase Inhibitor-α (5-22) amide (human, mouse, rabbit, rat), CAS : 100853-58-5 from ruixi.It is a cAMP-dependent protein kinase inhibitor. |
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R-M-736 |
CART (55-76) (rat) trifluoroacetate salt |
CART (55-76) (rat) trifluoroacetate salt,CAS : 1815618-15-5 from ruixi.Intracerebroventricular administration of this CART fragment inhibited normal and NPY-induced feeding in rats whereas injection of an antibody to it stimulated feeding. The anorexigenic fragment is also called CART 82-103. |
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