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R-R-0192 Cupper(II) tetramethoxyphenylporphyrin CAS. 24249-30-7 Cupper(II) tetramethoxyphenylporphyrin/5,10,15,20-Tetrakis(3-methoxyphenyl)porphyrinatonickel/ CAS. 24249-30-7 is a complex compound consisting of a copper atom coordinated with a tetramethoxyphenylporphyrin ligand. In Cu(II) tetramethoxyphenylporphyrin, the central copper atom is coordinated with the four nitrogen atoms of the porphyrin ring, forming a square planar geometry. The four methoxyphenyl groups are attached to the pyrrole units of the porphyrin ring, providing additional stability to the complex. This compound is commonly used in chemical research and catalysis due to its unique coordination properties and ability to interact with other molecules. price>
R-XASYS-00193 N-tert-Butyl-α-phenylnitrone,cas:3376-24-7 N-tert-Butyl- α- Phenylnitrone is a nitrone-based free radical scavenger that can form nitric oxide spin adducts. N-tert-Butyl- α- Phenylnitrone inhibits the catalytic activity of COX2. N-tert-Butyl- α- Phenylnitrone has effective ROS clearance, anti-inflammatory, neuroprotective, anti-aging and anti diabetes effects, and can penetrate the blood brain barrier. price>
R-R-0193 BSA-glucocorticoid BSA-glucocorticoid/Bovine serum albumin-glucocorticoid refers to a conjugate of glucocorticoid hormone (such as cortisol or dexamethasone) covalently linked to bovine serum albumin (BSA).BSA-glucocorticoid conjugates can provide important insights into the pharmacokinetics and pharmacodynamics of glucocorticoids, allowing researchers to better understand their interactions with cells and tissues. Additionally, these conjugates can be utilized in the development of new drug delivery systems and targeted therapies. price>
R-XASYS-00194 CL097,cas:1026249-18-2 CL097 is an effective TLR7 and TLR8 agonist that can induce proinflammatory cytokines in macrophages. CL097 induces NADPH oxidase activation, leading to an increase in fMLF stimulated ROS production. price>
R-R-0194 TPP-paclitaxel TPP-paclitaxel refers to the conjugate of paclitaxel, a commonly used chemotherapy drug, with TPP (triphenylphosphonium) as a targeting moiety.The selective accumulation of TPP-paclitaxel in mitochondria allows for increased drug concentration at the site of action, enhancing its effectiveness and reducing systemic toxicity. This targeted delivery approach has shown promise in preclinical studies for improving the anti-cancer activity of paclitaxel. price>
R-XASYS-00195 11-oxo-mogroside V,cas:126105-11-1 11-oxo-mogroside V(C60H100O29,1285.42) is a natural sweetener with strong antioxidant activity. 11-oxo-mogroside V has a significant inhibitory effect on active oxygen species, acting on O2 -, H2O2, and * OH, with an EC50 of 4.79, 16.52, and 146.17, respectively μ g/mL price>
R-R-0195 2-Iminothiolane hydrochloride CAS 4781-83-3 2-Iminothiolane hydrochloride (2IT) is a widely employed organosulfur compound in scientific research. Its primary application lies in synthesizing other compounds and conducting in vivo and in vitro studies, exploring biochemical and physiological impacts. Despite its potential benefits and drawbacks in laboratory experiments, 2IT continues to be of interest for various scientific pursuits.2IT finds utility in both in vivo studies conducted on animals and in vitro studies using tissue cultures or cell cultures. These studies delve into various scientific aspects, such as exploring biochemical and physiological effects. price>
R-XASYS-00196 Simvastatin acid ammonium,cas:139893-43-9 Simvastatin acid (Tenivastatin) ammonium is an effective inhibitor of HMG-CoA reductase (HMGCR). Simvastatin acid ammonium reduces the production of reactive oxygen species (ROS) mediated by indophenol sulfate. Simvastatin acid ammonium can also regulate OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with OATP3A1 gene. price>
R-R-0196 TAMRA oleic acid TAMRA oleic acid refers to the conjugation of the fluorescent dye TAMRA (Tetramethylrhodamine) with oleic acid, a common unsaturated fatty acid. TAMRA-oleic acid conjugates find applications in various research areas, including lipid metabolism, membrane dynamics, and cellular trafficking. They can be used in fluorescence microscopy, flow cytometry, and other imaging techniques to study lipid dynamics, lipid-protein interactions, and lipid-related diseases. price>
R-XASYS-00197 Bigelovin,cas:3668-14-2 Bigelovin(C17H20O5,304.34) is a sesquiterpene lactone that can be isolated from Sunflower and is a selective retinoin X receptorα(retinoid X receptorα) An agonist. Bigelovin can exert its anti-tumor activity by inducing apoptosis and autophagy. Bigelovin regulates the mTOR signal pathway by inhibiting ROS generation. price>
R-R-0197 Hydroxy-PEG2-CH2COOH cas 51951-04-3 Hydroxy-PEG2-CH2CO2H, sodium salt linker contains a hydroxyl group with a terminal carboxylic acid. The terminal carboxylic acid readily reacts with primary and secondary amine under EDC, DCC, HATU or other amide coupling conditions to form a stable amide bond. The PEG spacer increases the aqueous solubility of the resulting compound. The hydroxyl group can be further functionalized for bioconjugation purposes. price>
R-XASYS-00198 Bixin,cas:6983-79-5 Bixin (BX), isolated from the seeds of Bixa orellana, is a carotenoid, possessing anti-inflammatory, anti-tumor and anti-oxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation and reactive oxygen species (ROS) generation. price>
R-R-0198 Cy5-mannan Cy5-mannan/Cyanine5-mannan is a fluorescent dye-conjugated form of mannose, a type of sugar. It is used in various biological assays to detect and visualize mannose-binding proteins or to study mannose-dependent biological processes. The Cy5 moiety allows for easy detection of the labeled mannose using fluorescence microscopy or flow cytometry. This labeling strategy facilitates the study of mannose-related biological events in cells and tissues. price>
R-XASYS-00199 Pyocyanin,cas:85-66-5 Pyocyanine is a toxic, population sensitive (QS) controlled metabolite produced by Pseudomonas aeruginosa. Pyocyanin is a redox active compound that promotes the production of reactive oxygen species (ROS). Pyocyanin also has antibacterial properties and increases its adaptability to compete with other bacterial species. price>
R-R-0199 FITC Whey Protein FITC Whey Protein/Fluorescein Whey Protein is a conjugate formed by attaching fluorescein isothiocyanate (FITC), a fluorescent dye, to whey protein.FITC Whey Protein is commonly used as a fluorescent probe in various biological applications. It can be used to study protein uptake, localization, and trafficking in cells or tissues. FITC-labeled proteins are widely utilized tools in biological research and diagnostics for their ability to provide visual and quantitative information about the distribution, dynamics, and interaction of proteins within biological systems. price>
R-0080 DSPE-PEG-CY5.5 DSPE-PEG2k-CY5.5, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-Cyanine5.5(sodium salt) price>
R-XASYS-00200 Octahydrocurcumin,cas:36062-07-4 Octahydrocurcumin is a hydrogenated derivative of curcumin and a metabolite of curcumin. It scavenges DPPH radicals in a cell-free assay (IC50 = 12.3 µM) price>
R-R-0200 Phytanic Acid CAS 14721-66-5 Phytanic acid is a fatty acid metabolite of chlorophyll that acts as a ligand of retinoid X receptors (RXRs) and peroxisome proliferator-activated receptors (PPARs) and is known to regulate glucose metabolism. Phytanic acid also plays a role in disorders of peroxisomal metabolism such as Refsum disease. This compound induces apoptosis by uncoupling oxidative phosphorylation, stimulating ROS generation, and activating the free fatty acid receptor GPR40 to alter intracellular Ca2+ levels. price>
R-0226 DSPE-PEG-NOTA DSPE-PEG-NOTA,1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol) -NOTA (sodium salt) price>
R-XASYS-00201 Purpurin 18,cas:25465-77-4 Purpurin 18, a derivative of chlorophyll, is an interesting dihydroporphyrin for generating photosensitizers price>